STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA1991Similar to Yersinia pestis hypothetical protein ypo2340 or y1992 SWALL:Q8ZE44 (EMBL:AJ414152) (256 aa) fasta scores: E(): 5.7e-69, 73.93% id in 234 aa, and to Shigella dysenteriae YcjI SWALL:Q9LA26 (EMBL:AF153317) (262 aa) fasta scores: E(): 1.4e-67, 70.08% id in 234 aa. (239 aa)    
Predicted Functional Partners:
ECA1841
Similar to Escherichia coli hypothetical protein ydiv or b1707 SWALL:YDIV_ECOLI (SWALL:P76204) (237 aa) fasta scores: E(): 3.5e-23, 36.17% id in 235 aa, and to Shigella flexneri orf, conserved hypothetical protein ydiv or sf1524 SWALL:AAN43114 (EMBL:AE015175) (237 aa) fasta scores: E(): 3.1e-22, 35.74% id in 235 aa.
  
     0.762
wecH
Putative membrane protein; Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units.
  
     0.738
ECA2552
Similar to Yersinia pestis hypothetical protein Ypo1401 SWALL:Q8ZGA3 (EMBL:AJ414148) (297 aa) fasta scores: E(): 4.9e-98, 73.4% id in 297 aa, and to Salmonella typhimurium mukf protein stm0989 SWALL:Q8ZQB9 (EMBL:AE008742) (297 aa) fasta scores: E(): 2e-77, 58.78% id in 296 aa.
  
     0.671
mtlR
Mannitol operon repressor; Similar to Escherichia coli, and Escherichia coli O6 mannitol operon repressor MtlR or b3601 or c4418 SWALL:MTLR_ECOLI (SWALL:P36563) (195 aa) fasta scores: E(): 2.6e-47, 74.15% id in 178 aa.
  
     0.659
ECA2388
Similar to Yersinia pestis putative membrane protein ypo1755 or y2554 SWALL:AAM86109 (EMBL:AJ414150) (153 aa) fasta scores: E(): 3e-41, 73.02% id in 152 aa, and to Escherichia coli, and Escherichia coli O6 hypothetical protein yobd or b1820 or c2227 SWALL:YOBD_ECOLI (SWALL:P76263) (152 aa) fasta scores: E(): 8.8e-33, 57.89% id in 152 aa.
  
     0.625
flk
Cell division protein; Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor FlgM upon sensing ring completion or hook elongation. Flk could inhibit FlgM secretion by acting as a braking system for the flagellar-associated type III secretion system.
  
     0.616
rcsF
Stimulator of colanic acid capsule synthesis; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family.
  
     0.600
ECA1753
Similar to Yersinia pestis hypothetical protein Ypo1437 SWALL:Q8ZG75 (EMBL:AJ414148) (211 aa) fasta scores: E(): 7.1e-38, 53.36% id in 208 aa, and to Escherichia coli hypothetical protein yccr or b0959 SWALL:YCCR_ECOLI (SWALL:P75869) (209 aa) fasta scores: E(): 9.7e-27, 42.78% id in 194 aa.
  
     0.563
tpx
Thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.
       0.558
alaE
Putative membrane protein; Exports L-alanine; Belongs to the AlaE exporter family.
  
     0.557
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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