STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA2004Putative lipoprotein; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri hypothetical protein ynbe or b1382 or c1829 or sf1816 SWALL:YNBE_ECOLI (SWALL:P76075) (61 aa) fasta scores: E(): 2.7e-10, 73.21% id in 56 aa, and to Salmonella typhimurium, and Salmonella typhi putative outer membrane lipoprotein ynbe or stm1645 or sty1424 SWALL:Q8XEM6 (EMBL:AE008772) (63 aa) fasta scores: E(): 1.5e-09, 60.65% id in 61 aa. (76 aa)    
Predicted Functional Partners:
ECA2003
Putative exported protein; Similar to Yersinia pestis hypothetical protein y2005 SWALL:AAM85571 (EMBL:AE013803) (898 aa) fasta scores: E(): 1e-188, 52.6% id in 865 aa, and to Escherichia coli O6 hypothetical protein ydbh or c1828 SWALL:AAN80292 (EMBL:AE016760) (879 aa) fasta scores: E(): 2.9e-148, 44.01% id in 861 aa.
 
   
 0.842
ECA3206
Transcriptional regulator; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri sugar fermentation stimulation protein B SfsB or Nlp or Sfs7 or b3188 or c3946 or z4551 or ecs4067 or sf3228 SWALL:SFSB_ECOLI (SWALL:P18837) (92 aa) fasta scores: E(): 3.1e-15, 71.21% id in 66 aa. Also similar to ECA0513 (91.139% id. in 79 aa overlap), and to ECA0966 (85.714% id. in 70 aa overlap), and to ECA0686 (76.119% id. in 67 aa overlap.).
  
     0.612
ECA0966
Transcriptional regulator; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri sugar fermentation stimulation protein B SfsB or Nlp or Sfs7 or b3188 or c3946 or z4551 or ecs4067 or sf3228 SWALL:SFSB_ECOLI (SWALL:P18837) (92 aa) fasta scores: E(): 4.3e-16, 75% id in 64 aa, and to Salmonella typhi transcriptional regulatory protein CII or sty4673 SWALL:Q8Z1B7 (EMBL:AL627283) (73 aa) fasta scores: E(): 3e-19, 79.41% id in 68 aa. Also similar to ECA0513 (91.139% id. in 79 aa overlap), and to ECA3206 (85.714% id. in 70 aa overlap), and to ECA068 [...]
  
     0.609
ECA0513
Putative phage transcriptional regulator; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri sugar fermentation stimulation protein B SfsB or Nlp or sfs7 or b3188 or c3946 or z4551 or ecs4067 or sf3228 SWALL:SFSB_ECOLI (SWALL:P18837) (92 aa) fasta scores: E(): 5.5e-15, 71.87% id in 64 aa, and to Bacteriophage Mu DNA-binding protein Ner or CII or 2 SWALL:NER_BPMU (SWALL:P06020) (74 aa) fasta scores: E(): 3.8e-13, 64.61% id in 65 aa. Also similar to ECA0686 (71.233% id. in 73 aa overlap), and to ECA0966 (91.139% id. in 79 aa overlap), and to [...]
  
     0.608
sfsB
Sugar fermentation stimulation protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri sugar fermentation stimulation protein B SfsB or Nlp or sfs7 or b3188 or c3946 or z4551 or ecs4067 or sf3228 SWALL:SFSB_ECOLI (SWALL:P18837) (92 aa) fasta scores: E(): 5.7e-20, 70.88% id in 79 aa. Also similar to ECA0513 (71.233% id. in 73 aa overlap), and to ECA0966 (72.368% id. in 76 aa overlap), and to ECA3206 (76.119% id. in 67 aa overlap.).
  
     0.573
sulA
Cell division inhibitor; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
  
     0.537
ECA3472
Similar to Yersinia pestis hypothetical protein ypo3242 or y0948 SWALL:Q8ZBY8 (EMBL:AJ414156) (257 aa) fasta scores: E(): 9.9e-101, 86.22% id in 254 aa, and to Escherichia coli hypothetical protein yafj or b0223 SWALL:YAFJ_ECOLI (SWALL:Q47147) (255 aa) fasta scores: E(): 4.9e-95, 82.35% id in 255 aa.
  
     0.477
sbcD
Exonuclease subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
  
     0.407
ECA1333
Similar to Yersinia pestis hypothetical protein ypo2637 or y1211 SWALL:AAM84787 (EMBL:AJ414153) (95 aa) fasta scores: E(): 2e-28, 92.39% id in 92 aa, and to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein ybfe or b0685 or z0834 or ecs0716 or sf0608 SWALL:YBFE_ECOLI (SWALL:P75735) (120 aa) fasta scores: E(): 5.4e-25, 81.72% id in 93 aa.
  
     0.406
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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