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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA2046Putative bifunctional enzyme including aminotransferase and chitin synthase; Its N-terminal half is similar to several aminotransferases including Escherichia coli VioA SWALL:Q9XCW4 (EMBL:AF125322) (371 aa) fasta scores: E(): 1.6e-29, 32.31% id in 359 aa, and to Streptomyces globisporus amino transferase SWALL:AAL06659 (EMBL:AY048670) (410 aa) fasta scores: E(): 9.5e-29, 32.32% id in 396 aa. Its C-terminal half is similar to many chitin synthases such as Saprolegnia monoica chitin synthase chS SWALL:CHS_SAPMO (SWALL:P48017) (886 aa) fasta scores: E(): 6.2e-20, 24% id in 525 aa, and to [...] (1026 aa)    
Predicted Functional Partners:
wcaJ
Putative capsular polysaccharide biosynthesis protein; Similar to Escherichia coli putative colanic biosynthesis UDP-glucose lipid carrier transferase WcaJ or b2047 SWALL:WCAJ_ECOLI (SWALL:P71241) (464 aa) fasta scores: E(): 6.8e-69, 43.62% id in 463 aa, and to Klebsiella pneumoniae probable CPS biosynthesis glycosyltransferase SWALL:YC14_KLEPN (SWALL:Q48460) (465 aa) fasta scores: E(): 1e-69, 43.95% id in 455 aa.
 
  
 0.898
rfbP
Similar to Salmonella typhimurium undecaprenyl-phosphate galactosephosphotransferase RfbP or stm2082 SWALL:RFBP_SALTY (SWALL:P26406) (476 aa) fasta scores: E(): 3e-129, 64.65% id in 464 aa, and to Erwinia amylovora UDP-galactose-lipid carrier transferase amsG SWALL:AMSG_ERWAM (SWALL:Q46628) (477 aa) fasta scores: E(): 2.8e-131, 66.3% id in 466 aa.
 
  
 0.895
ECA2045
Putative NAD dependent epimerase/dehydratase; Similar to Streptomyces glaucescens StrP protein SWALL:Q54262 (EMBL:X78974) (358 aa) fasta scores: E(): 8.5e-33, 35.98% id in 339 aa, and to Agrobacterium tumefaciens udp-glucose 4-epimerase gale or atu4801 or agr_l_161 SWALL:Q8U6K6 (EMBL:AE009408) (378 aa) fasta scores: E(): 3.2e-31, 33.81% id in 343 aa.
 
  
 0.837
ECA2047
Putative exported protein; Similar to Ralstonia solanacearum hypothetical protein rsc1651 or rs04028 SWALL:Q8XYV5 (EMBL:AL646065) (394 aa) fasta scores: E(): 5.6e-36, 34.18% id in 392 aa, and to Caulobacter crescentus hypothetical protein Cc1979 SWALL:Q9A6V4 (EMBL:AE005871) (407 aa) fasta scores: E(): 1.3e-16, 25.77% id in 388 aa.
       0.668
arnA
Probable formyl transferase; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
 
  
 0.667
rffG
Similar to Escherichia coli dTDP-glucose 4,6-dehydratase RffG or b3788 SWALL:RFFG_ECOLI (SWALL:P27830) (355 aa) fasta scores: E(): 6.4e-119, 83% id in 353 aa; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
 
  
 0.653
ECA2048
Putative exported protein; Similar to Ralstonia solanacearum probable signal peptide protein rsc1650 or rs04027 SWALL:Q8XYV6 (EMBL:AL646065) (538 aa) fasta scores: E(): 1.4e-41, 34.04% id in 376 aa, and to Rhizobium loti hypothetical protein Mll5453 SWALL:Q98BS0 (EMBL:AP003006) (508 aa) fasta scores: E(): 1.6e-09, 25.22% id in 452 aa.
       0.637
arnC
Probable glycosyl transferase; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
 
  
 0.610
wecC
UDP-N-acetyl-D-mannosamine dehydrogenase; Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA); Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily.
 
  
 0.577
wecB
UDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.
  
  
 0.577
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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