STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hrpLSigma factor; Similar to Erwinia chrysanthemi HrpL WALL:Q8KUM5 (EMBL:AF448202) (184 aa) fasta scores: E(): 9.4e-40, 71.42% id in 168 aa, and to Erwinia pyrifoliae sigma factor hrpL SWALL:CAD27523 (EMBL:AJ438881) (182 aa) fasta scores: E(): 1.9e-31, 56.97% id in 165 aa; Belongs to the sigma-70 factor family. ECF subfamily. (180 aa)    
Predicted Functional Partners:
hrpJ
Type III secretion protein; Similar to Pectobacterium carotovorum subsp. atrosepticum secretion protein HrpJ type III HrpJ SWALL:Q8KM25 (EMBL:AJ496800) (402 aa) fasta scores: E(): 1.2e-121, 90.79% id in 402 aa, and to Erwinia chrysanthemi HrpJ WALL:AAO34609 (EMBL:AY169276) (393 aa) fasta scores: E(): 2.3e-80, 64.59% id in 387 aa.
 
  
 0.774
hrpX
Two-component sensor kinase; Similar to Erwinia chrysanthemi HrpX SWALL:Q8KUM4 (EMBL:AF448202) (450 aa) fasta scores: E(): 3.4e-115, 68.25% id in 441 aa, and to Erwinia amylovora sensor kinase HrpX SWALL:Q9X3S8 (EMBL:AF083877) (494 aa) fasta scores: E(): 9.5e-100, 56.13% id in 481 aa.
  
  
 0.749
rseA
sigma-E factor negative regulator; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases [...]
  
 
 0.695
hrcQ
Type III secretion protein; Similar to Erwinia amylovora HrcQ SWALL:Q46645 (EMBL:L25828) (338 aa) fasta scores: E(): 1.8e-11, 34.59% id in 370 aa, and to Pantoea agglomerans HrcQb protein SWALL:Q47855 (EMBL:X99768) (108 aa) fasta scores: E(): 9.8e-11, 46.22% id in 106 aa.
  
 
 0.691
hrpY
Two-component response regulator; Similar to Erwinia chrysanthemi HrpY SWALL:Q8KUM3 (EMBL:AF448202) (213 aa) fasta scores: E(): 6.8e-57, 75.94% id in 212 aa, and to Erwinia amylovora response regulator HrpY SWALL:Q9X3S9 (EMBL:AF083877) (213 aa) fasta scores: E(): 1.3e-51, 69.34% id in 212 aa.
  
  
 0.658
hrpP
Type III secretion protein; Similar to Erwinia amylovora HrpP SWALL:Q46644 (EMBL:L25828) (158 aa) fasta scores: E(): 1.6e-06, 36.6% id in 112 aa, and to Pantoea agglomerans HrcQa protein hrcQa SWALL:Q47853 (EMBL:X99768) (157 aa) fasta scores: E(): 8e-06, 28.81% id in 118 aa.
     
 0.648
hrpS
Sigma-54-dependent enhancer-binding protein; Similar to Erwinia chrysanthemi HrpS SWALL:Q8KUM2 (EMBL:AF448202) (327 aa) fasta scores: E(): 6.8e-80, 74.67% id in 304 aa, and to Erwinia amylovora sigma-54-dependent enhancer-binding protein HrpS SWALL:Q9X3T0 (EMBL:AF083877) (324 aa) fasta scores: E(): 6.8e-66, 61.99% id in 321 aa.
 
   
 0.647
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.626
ECA3886
Putative membrane protein; Similar to the C-terminal region of many including Pseudomonas aeruginosa hypothetical protein Pa2870 SWALL:Q9HZX6 (EMBL:AE004713) (525 aa) fasta scores: E(): 1.9e-17, 39.39% id in 165 aa, and to Shewanella oneidensis ggdef domain protein so4457 SWALL:AAN57422 (EMBL:AE015878) (485 aa) fasta scores: E(): 2.1e-17, 39.03% id in 187 aa.
   
 
 0.626
ECA0705
Partial CDS. Similar to an internal region of Agrobacterium tumefaciens non-ribosomal peptide synthetase MtaD or atu3682 or agr_l_2311 SWALL:Q8U9P4 (EMBL:AE009297) (2399 aa) fasta scores: E(): 0.00074, 32.99% id in 97 aa, and to Anabaena sp. peptide synthetase all2648 SWALL:Q8YTR5 (EMBL:AP003590) (2588 aa) fasta scores: E(): 0.0032, 34.4% id in 93 aa.
  
  
 0.552
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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