STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hrpXTwo-component sensor kinase; Similar to Erwinia chrysanthemi HrpX SWALL:Q8KUM4 (EMBL:AF448202) (450 aa) fasta scores: E(): 3.4e-115, 68.25% id in 441 aa, and to Erwinia amylovora sensor kinase HrpX SWALL:Q9X3S8 (EMBL:AF083877) (494 aa) fasta scores: E(): 9.5e-100, 56.13% id in 481 aa. (478 aa)    
Predicted Functional Partners:
hrpY
Two-component response regulator; Similar to Erwinia chrysanthemi HrpY SWALL:Q8KUM3 (EMBL:AF448202) (213 aa) fasta scores: E(): 6.8e-57, 75.94% id in 212 aa, and to Erwinia amylovora response regulator HrpY SWALL:Q9X3S9 (EMBL:AF083877) (213 aa) fasta scores: E(): 1.3e-51, 69.34% id in 212 aa.
 
 0.991
rcsC
Two-component system sensor protein; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
  
 
 0.967
rcsB
Two-component response regulator; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
 
 
 0.967
arcB
Similar to Escherichia coli, and Shigella flexneri aerobic respiration control sensor protein ArcB or b3210 or sf3250 SWALL:ARCB_ECOLI (SWALL:P22763) (778 aa) fasta scores: E(): 8.6e-180, 75.88% id in 788 aa, and to Yersinia pestis aerobic respiration control sensor/response regulatory protein ArcB SWALL:Q8ZB69 (EMBL:AJ414157) (778 aa) fasta scores: E(): 3.6e-190, 80.71% id in 788 aa.
 
 
 0.966
rpfA
Two-component sensor kinase and response regulator; Similar to Pectobacterium carotovorum subsp. carotovorum sensor/regulator protein RpfA SWALL:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 92.88% id in 928 aa, and to Pectobacterium carotovorum subsp. carotovorum sensory kinase ExpS SWALL:O32556 (EMBL:Y13670) (928 aa) fasta scores: E(): 0, 95.36% id in 928 aa.
 
 
 0.965
ECA3886
Putative membrane protein; Similar to the C-terminal region of many including Pseudomonas aeruginosa hypothetical protein Pa2870 SWALL:Q9HZX6 (EMBL:AE004713) (525 aa) fasta scores: E(): 1.9e-17, 39.39% id in 165 aa, and to Shewanella oneidensis ggdef domain protein so4457 SWALL:AAN57422 (EMBL:AE015878) (485 aa) fasta scores: E(): 2.1e-17, 39.03% id in 187 aa.
  
 
 0.959
uhpA
Two-component system response regulator protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri transcriptional regulatory protein UhpA or b3669 or c4593 or z5159 or ecs4606 or sf3792 SWALL:UHPA_ECOLI (SWALL:P10940) (196 aa) fasta scores: E(): 1.2e-29, 48.98% id in 196 aa.
 
 
 0.944
narP
Similar to Escherichia coli nitrate/nitrite response regulator protein NarP or b2193 SWALL:NARP_ECOLI (SWALL:P31802) (215 aa) fasta scores: E(): 3e-46, 65.72% id in 213 aa.
 
 
 0.943
narL
Nitrate/nitrite response regulator; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri nitrate/nitrite response regulator protein NarL or FrdR or b1221 or c1681 or z1996 or ecs1726 or sf1224 SWALL:NARL_ECOLI (SWALL:P10957) (216 aa) fasta scores: E(): 2.2e-60, 80.46% id in 215 aa.
 
 0.940
expA
Two-component response regulator; Similar to Erwinia carotovora ExpA protein SWALL:O50326 (EMBL:X95564) (218 aa) fasta scores: E(): 1.3e-77, 98.62% id in 218 aa, and to Escherichia coli, and Shigella flexneri response regulator UvrY or b1914 or sf1957 SWALL:UVRY_ECOLI (SWALL:P07027) (218 aa) fasta scores: E(): 3.5e-65, 83.87% id in 217 aa. The Erwinia carotovora ExpA is involved in the global control of virulence.
 
 0.938
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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