STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hrpSSigma-54-dependent enhancer-binding protein; Similar to Erwinia chrysanthemi HrpS SWALL:Q8KUM2 (EMBL:AF448202) (327 aa) fasta scores: E(): 6.8e-80, 74.67% id in 304 aa, and to Erwinia amylovora sigma-54-dependent enhancer-binding protein HrpS SWALL:Q9X3T0 (EMBL:AF083877) (324 aa) fasta scores: E(): 6.8e-66, 61.99% id in 321 aa. (354 aa)    
Predicted Functional Partners:
ECA3886
Putative membrane protein; Similar to the C-terminal region of many including Pseudomonas aeruginosa hypothetical protein Pa2870 SWALL:Q9HZX6 (EMBL:AE004713) (525 aa) fasta scores: E(): 1.9e-17, 39.39% id in 165 aa, and to Shewanella oneidensis ggdef domain protein so4457 SWALL:AAN57422 (EMBL:AE015878) (485 aa) fasta scores: E(): 2.1e-17, 39.03% id in 187 aa.
  
 0.927
rpfA
Two-component sensor kinase and response regulator; Similar to Pectobacterium carotovorum subsp. carotovorum sensor/regulator protein RpfA SWALL:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 92.88% id in 928 aa, and to Pectobacterium carotovorum subsp. carotovorum sensory kinase ExpS SWALL:O32556 (EMBL:Y13670) (928 aa) fasta scores: E(): 0, 95.36% id in 928 aa.
  
 0.876
arcB
Similar to Escherichia coli, and Shigella flexneri aerobic respiration control sensor protein ArcB or b3210 or sf3250 SWALL:ARCB_ECOLI (SWALL:P22763) (778 aa) fasta scores: E(): 8.6e-180, 75.88% id in 788 aa, and to Yersinia pestis aerobic respiration control sensor/response regulatory protein ArcB SWALL:Q8ZB69 (EMBL:AJ414157) (778 aa) fasta scores: E(): 3.6e-190, 80.71% id in 788 aa.
  
 0.870
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.856
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
    
 0.758
hrpX
Two-component sensor kinase; Similar to Erwinia chrysanthemi HrpX SWALL:Q8KUM4 (EMBL:AF448202) (450 aa) fasta scores: E(): 3.4e-115, 68.25% id in 441 aa, and to Erwinia amylovora sensor kinase HrpX SWALL:Q9X3S8 (EMBL:AF083877) (494 aa) fasta scores: E(): 9.5e-100, 56.13% id in 481 aa.
   
 0.739
hrpY
Two-component response regulator; Similar to Erwinia chrysanthemi HrpY SWALL:Q8KUM3 (EMBL:AF448202) (213 aa) fasta scores: E(): 6.8e-57, 75.94% id in 212 aa, and to Erwinia amylovora response regulator HrpY SWALL:Q9X3S9 (EMBL:AF083877) (213 aa) fasta scores: E(): 1.3e-51, 69.34% id in 212 aa.
   
 0.716
glnL
Nitrogen regulation two-component system, histidine kinase; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri nitrogen regulation protein nr(II) GlnL or NtrB or GlnR SWALL:AAN45374 (EMBL:X05173) (349 aa) fasta scores: E(): 1.2e-108, 84.81% id in 349 aa.
 
 0.709
hrpL
Sigma factor; Similar to Erwinia chrysanthemi HrpL WALL:Q8KUM5 (EMBL:AF448202) (184 aa) fasta scores: E(): 9.4e-40, 71.42% id in 168 aa, and to Erwinia pyrifoliae sigma factor hrpL SWALL:CAD27523 (EMBL:AJ438881) (182 aa) fasta scores: E(): 1.9e-31, 56.97% id in 165 aa; Belongs to the sigma-70 factor family. ECF subfamily.
 
   
 0.647
fliM
Flagellar motor switch protein; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
  
 
 0.606
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.