Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ECA2167Putative inositol monophosphatase; Similar to Rhizobium loti N-amidino-scyllo-inosamine-4-phosphate phosphatase mll6642 SWALL:Q988Q3 (EMBL:AP003009) (239 aa) fasta scores: E(): 3.3e-47, 56.39% id in 211 aa, and to Agrobacterium rhizogenes Riorf69 protein riorf69 SWALL:Q9KWB5 (EMBL:AB039932) (263 aa) fasta scores: E(): 4e-44, 48.3% id in 265 aa. (265 aa)    
Predicted Functional Partners:
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
 
 0.975
hisB
Similar to Escherichia coli histidine biosynthesis bifunctional protein HisB [includes: histidinol-phosphatase and imidazoleglycerol-phosphate dehydratase] HisB or b2022 SWALL:HIS7_ECOLI (SWALL:P06987) (355 aa) fasta scores: E(): 1.6e-119, 82.81% id in 355 aa.
  
 
 0.975
hisC
Similar to Escherichia coli histidinol-phosphate aminotransferase HisC or b2021 SWALL:HIS8_ECOLI (SWALL:P06986) (356 aa) fasta scores: E(): 1e-103, 75.07% id in 349 aa; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
 
 0.973
ECA2250
Putative aminotransferase; Similar to Xanthomonas campestris histidinol-phosphate aminotransferase hisc or xcc3275 SWALL:Q8P5R1 (EMBL:AE012444) (399 aa) fasta scores: E(): 2.9e-27, 31.33% id in 367 aa, and to Pseudomonas fluorescens putative aminotransferase qbsB SWALL:AAL65284 (EMBL:AY072690) (363 aa) fasta scores: E(): 1.1e-26, 32.2% id in 354 aa.
  
 
 0.950
nusG
Transcription antitermination protein; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination; Bel [...]
   
 
 0.761
nusA
N utilization substance protein A; Participates in both transcription termination and antitermination.
   
   0.731
rpoZ
DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
   0.699
rpoC
DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.696
rpoB
DNA-directed RNA polymerase, beta-subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.692
ECA2168
Similar to Listeria monocytogenes hypothetical protein Lmo0406 SWALL:Q8Y9W3 (EMBL:AL591975) (126 aa) fasta scores: E(): 3e-16, 43.3% id in 127 aa, and to Bacillus subtilis hypothetical protein YyaH SWALL:YYAH_BACSU (SWALL:P37516) (126 aa) fasta scores: E(): 8.2e-14, 36.22% id in 127 aa.
 
    0.640
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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