STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hemKProtein methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. (281 aa)    
Predicted Functional Partners:
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
 
 
 0.992
sirB2
Putative membrane protein; Similar to Escherichia coli protein SirB2 or b1213 SWALL:SIB2_ECOLI (SWALL:Q46755) (130 aa) fasta scores: E(): 2.3e-16, 44.61% id in 130 aa, and to Salmonella typhimurium, and Salmonella typhi protein SirB2 or stm1774 or sty1899 SWALL:SIB2_SALTY (SWALL:Q9XCQ2) (129 aa) fasta scores: E(): 4.7e-20, 55% id in 120 aa.
  
    0.903
hisS
histidyl-tRNA synthetase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 histidyl-tRNA synthetase hiss or b2514 or c3036 or z3777 or ecs3376 SWALL:SYH_ECOLI (SWALL:P04804) (423 aa) fasta scores: E(): 2.2e-136, 81.75% id in 422 aa.
  
  
 0.802
sirB1
Putative regulator; Similar to Escherichia coli, and Escherichia coli O157:H7 protein SirB1 or b1214 or z1985 or ecs1719 SWALL:SIB1_ECOLI (SWALL:P20101) (269 aa) fasta scores: E(): 8.3e-71, 66.17% id in 269 aa.
       0.793
cpdB
Similar to Escherichia coli 2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor CpdB or b4213 SWALL:CN16_ECOLI (SWALL:P08331) (647 aa) fasta scores: E(): 9.6e-198, 76.68% id in 639 aa; Belongs to the 5'-nucleotidase family.
      
 0.789
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
     
 0.744
prfB
Putative peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
 
  
 0.704
kdsA
2-dehydro-3-deoxyphosphooctonate aldolase; Similar to Escherichia coli, and Shigella flexneri 2-dehydro-3-deoxyphosphooctonate aldolase KdsA or b1215 or sf1218 SWALL:KDSA_ECOLI (SWALL:P17579) (284 aa) fasta scores: E(): 5.2e-99, 90.45% id in 283 aa; Belongs to the KdsA family.
       0.656
gcvP
Putative glycine cleavage system P protein (glycine dehydrogenase [decarboxylating]); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
  0.641
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
  0.606
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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