STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sirB2Putative membrane protein; Similar to Escherichia coli protein SirB2 or b1213 SWALL:SIB2_ECOLI (SWALL:Q46755) (130 aa) fasta scores: E(): 2.3e-16, 44.61% id in 130 aa, and to Salmonella typhimurium, and Salmonella typhi protein SirB2 or stm1774 or sty1899 SWALL:SIB2_SALTY (SWALL:Q9XCQ2) (129 aa) fasta scores: E(): 4.7e-20, 55% id in 120 aa. (131 aa)    
Predicted Functional Partners:
sirB1
Putative regulator; Similar to Escherichia coli, and Escherichia coli O157:H7 protein SirB1 or b1214 or z1985 or ecs1719 SWALL:SIB1_ECOLI (SWALL:P20101) (269 aa) fasta scores: E(): 8.3e-71, 66.17% id in 269 aa.
  
  
 0.923
hemK
Protein methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
  
    0.883
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
  
    0.800
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
       0.688
hemX
Similar to Escherichia coli putative uroporphyrin-III C-methyltransferase HemX or b3803 SWALL:HEMX_ECOLI (SWALL:P09127) (393 aa) fasta scores: E(): 5.1e-71, 60.54% id in 370 aa.
  
  
  0.659
kdsA
2-dehydro-3-deoxyphosphooctonate aldolase; Similar to Escherichia coli, and Shigella flexneri 2-dehydro-3-deoxyphosphooctonate aldolase KdsA or b1215 or sf1218 SWALL:KDSA_ECOLI (SWALL:P17579) (284 aa) fasta scores: E(): 5.2e-99, 90.45% id in 283 aa; Belongs to the KdsA family.
       0.649
lolB
Outer-membrane lipoprotein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
 
     0.593
nirE
Similar to Paracoccus denitrificans uroporphyrin-III C-methyltransferase NirE SWALL:NIRE_PARDE (SWALL:Q51701) (287 aa) fasta scores: E(): 2.3e-41, 49.6% id in 256 aa, and to Vibrio cholerae uroporphyrin-III C-methyltransferase vc2561 SWALL:Q9KP18 (EMBL:AE004324) (299 aa) fasta scores: E(): 1.6e-48, 58.15% id in 239 aa; Belongs to the precorrin methyltransferase family.
     
  0.499
cysG1
Siroheme synthase [includes: uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
     
  0.499
cysG2
Siroheme synthase [includes: uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
     
  0.499
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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