STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sirB1Putative regulator; Similar to Escherichia coli, and Escherichia coli O157:H7 protein SirB1 or b1214 or z1985 or ecs1719 SWALL:SIB1_ECOLI (SWALL:P20101) (269 aa) fasta scores: E(): 8.3e-71, 66.17% id in 269 aa. (269 aa)    
Predicted Functional Partners:
sirB2
Putative membrane protein; Similar to Escherichia coli protein SirB2 or b1213 SWALL:SIB2_ECOLI (SWALL:Q46755) (130 aa) fasta scores: E(): 2.3e-16, 44.61% id in 130 aa, and to Salmonella typhimurium, and Salmonella typhi protein SirB2 or stm1774 or sty1899 SWALL:SIB2_SALTY (SWALL:Q9XCQ2) (129 aa) fasta scores: E(): 4.7e-20, 55% id in 120 aa.
  
  
 0.923
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
       0.782
hemK
Protein methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
       0.782
rcsF
Stimulator of colanic acid capsule synthesis; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family.
  
     0.722
ECA1753
Similar to Yersinia pestis hypothetical protein Ypo1437 SWALL:Q8ZG75 (EMBL:AJ414148) (211 aa) fasta scores: E(): 7.1e-38, 53.36% id in 208 aa, and to Escherichia coli hypothetical protein yccr or b0959 SWALL:YCCR_ECOLI (SWALL:P75869) (209 aa) fasta scores: E(): 9.7e-27, 42.78% id in 194 aa.
  
     0.696
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
       0.688
expM
Response regulator; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation.
  
   
 0.664
ECA3332
Similar to Yersinia pestis putative exported protein ypo3410 or y0776 SWALL:Q8ZBJ9 (EMBL:AJ414157) (115 aa) fasta scores: E(): 1.6e-30, 69.29% id in 114 aa, and to Escherichia coli, and Escherichia coli O6 hypothetical protein yacc precursor yacc or b0122 or c0151 SWALL:YACC_ECOLI (SWALL:P23838) (115 aa) fasta scores: E(): 1.6e-27, 64.34% id in 115 aa.
  
     0.661
kdsA
2-dehydro-3-deoxyphosphooctonate aldolase; Similar to Escherichia coli, and Shigella flexneri 2-dehydro-3-deoxyphosphooctonate aldolase KdsA or b1215 or sf1218 SWALL:KDSA_ECOLI (SWALL:P17579) (284 aa) fasta scores: E(): 5.2e-99, 90.45% id in 283 aa; Belongs to the KdsA family.
       0.649
ECA4405
Conserved hypothetical protein; Similar to Salmonella typhi putative ATP/GTP-binding protein sty3967 SWALL:Q8Z2M0 (EMBL:AL627280) (408 aa) fasta scores: E(): 1.1e-44, 61.39% id in 417 aa, and to Escherichia coli hypothetical protein yidr or b3689 SWALL:YIDR_ECOLI (SWALL:P31455) (416 aa) fasta scores: E(): 7.8e-40, 61.08% id in 406 aa.
  
     0.641
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.