STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
insGTransposase for insertion sequence element IS4 (partial); Similar to the N-terminal regions of several transposases including Escherichia coli transposase InsG for insertion sequence element IS4 InsG or b4278 SWALL:INSG_ECOLI (SWALL:P03835) (442 aa) fasta scores: E(): 1.6e-46, 74.32% id in 148 aa, and to Shigella flexneri IS4 orf s0243 SWALL:Q9AFL8 (EMBL:AF348706) (439 aa) fasta scores: E(): 1.6e-46, 74.32% id in 148 aa. (157 aa)    
Predicted Functional Partners:
ECA2195
Similar to the C-terminal regions of many including Escherichia coli transposase insg for insertion sequence element IS4 InsG or b4278 SWALL:INSG_ECOLI (SWALL:P03835) (442 aa) fasta scores: E(): 1.8e-36, 69.23% id in 143 aa.
 
     0.964
ECA2201
Putative integrase; Similar to the C-terminal regions of several including Comamonas acidovorans Orf4 SWALL:Q8RS31 (EMBL:AB049198) (323 aa) fasta scores: E(): 1.3e-42, 81.2% id in 133 aa, and to Synechococcus elongatus Tll0382 protein tll0382 SWALL:BAC07934 (EMBL:AP005370) (330 aa) fasta scores: E(): 6.9e-22, 53.98% id in 113 aa.
       0.737
chpA
Putative growth inhibitory protein; Similar to Escherichia coli, and Escherichia coli O157:H7 PemK-like protein 1 ChpA or MazF or ChpaK or b2782 or z4097 or ecs3642 SWALL:CHPA_ECOLI (SWALL:P33645) (111 aa) fasta scores: E(): 5.2e-31, 72.97% id in 111 aa, and to Deinococcus radiodurans ppgpp-regulated growth inhibitor chpa/mazf, putative dr0417 SWALL:Q9RX98 (EMBL:AE001901) (117 aa) fasta scores: E(): 5e-18, 48.21% id in 112 aa.
  
     0.672
chpR
Suppressor of growth inhibitory protein ChpA; Similar to Escherichia coli, and Escherichia coli O157:H7 PemI-like protein 1 ChpR or MazE or ChpaI or b2783 or z4098 or ecs3643 SWALL:CHPR_ECOLI (SWALL:P18534) (82 aa) fasta scores: E(): 4.6e-09, 38.55% id in 83 aa, and to Bacillus halodurans suppressor of ppgpp-regulated growth inhibitor bh3720 SWALL:Q9K6K9 (EMBL:AP001519) (81 aa) fasta scores: E(): 6.1e-05, 38.75% id in 80 aa.
  
     0.502
rcsF
Stimulator of colanic acid capsule synthesis; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family.
  
     0.498
ECA2203
Similar to Yersinia pestis putative exported protein ypo2305 or y2136 SWALL:Q8ZE77 (EMBL:AJ414151) (317 aa) fasta scores: E(): 2.4e-78, 69.9% id in 319 aa, and to Shigella flexneri orf, conserved hypothetical protein sf1625 SWALL:AAN43208 (EMBL:AE015183) (314 aa) fasta scores: E(): 8.2e-74, 67.82% id in 317 aa.
       0.478
expM
Response regulator; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation.
  
     0.445
fecA
iron(III) dicitrate transport protein; Similar to Escherichia coli iron FecA or b4291 SWALL:FECA_ECOLI (SWALL:P13036) (774 aa) fasta scores: E(): 0, 80.56% id in 782 aa, and to Pseudomonas aeruginosa FecA or pa3901 SWALL:Q9HXB2 (EMBL:AE004807) (784 aa) fasta scores: E(): 1.6e-196, 62.43% id in 788 aa.
  
     0.421
ECA0460
Similar to Yersinia pestis hypothetical protein ypo0911 SWALL:Y911_YERPE (SWALL:Q8ZHI2) (192 aa) fasta scores: E(): 1.2e-49, 70.76% id in 195 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein YgfB SWALL:YGFB_ECOLI (SWALL:P25533) (192 aa) fasta scores: E(): 4.4e-49, 70.25% id in 195 aa; Belongs to the UPF0149 family.
  
     0.420
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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