STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
srfCPutative virulence factor; Similar to Salmonella typhimurium SrfC or stm1595 SWALL:Q9KIJ8 (EMBL:AF231758) (714 aa) fasta scores: E(): 4.2e-23, 30.06% id in 795 aa, and to Yersinia pestis putative virulence factor y2123 SWALL:AAM85685 (EMBL:AE013815) (846 aa) fasta scores: E(): 2.9e-65, 55.12% id in 849 aa. (820 aa)    
Predicted Functional Partners:
srfB
Putative virulence effector protein; Similar to Salmonella typhimurium SrfB or stm1594 SWALL:Q9KIJ9 (EMBL:AF231758) (993 aa) fasta scores: E(): 0, 57.47% id in 997 aa, and to Yersinia pestis putative virulence factor ypo2290 SWALL:Q8ZE92 (EMBL:AJ414151) (1023 aa) fasta scores: E(): 2.1e-214, 73.8% id in 1027 aa.
 
  
 0.974
srfA
Putative virulence effector protein; Similar to Salmonella typhimurium, and Salmonella typhi SrfA or sty1472 SWALL:Q9KIK0 (EMBL:AF231758) (399 aa) fasta scores: E(): 2.4e-16, 41.06% id in 431 aa, and to Yersinia pestis putative virulence factor y2121 SWALL:AAM85682 (EMBL:AE013815) (477 aa) fasta scores: E(): 4.2e-29, 51.02% id in 488 aa.
 
     0.946
flk
Cell division protein; Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor FlgM upon sensing ring completion or hook elongation. Flk could inhibit FlgM secretion by acting as a braking system for the flagellar-associated type III secretion system.
  
     0.640
mtlR
Mannitol operon repressor; Similar to Escherichia coli, and Escherichia coli O6 mannitol operon repressor MtlR or b3601 or c4418 SWALL:MTLR_ECOLI (SWALL:P36563) (195 aa) fasta scores: E(): 2.6e-47, 74.15% id in 178 aa.
  
     0.597
ptrA
Similar to Escherichia coli protease III precursor PtrA or Ptr or b2821 SWALL:PTRA_ECOLI (SWALL:P05458) (962 aa) fasta scores: E(): 0, 63.68% id in 950 aa, and to Yersinia pestis protease III ptra or ypo1019 or ptr or y3165 SWALL:Q8ZH89 (EMBL:AJ414146) (962 aa) fasta scores: E(): 0, 68.02% id in 960 aa; Belongs to the peptidase M16 family.
  
   
 0.590
flgN
Flagella synthesis protein; Similar to Salmonella typhimurium, and Salmonella typhi flagella synthesis protein FlgN or stm1171 or sty1210 SWALL:FLGN_SALTY (SWALL:P37406) (140 aa) fasta scores: E(): 2.4e-14, 38.88% id in 144 aa, and to Yersinia enterocolitica flagella synthesis protein FlgN SWALL:FLGN_YEREN (SWALL:Q56854) (147 aa) fasta scores: E(): 6.2e-22, 46.85% id in 143 aa.
  
     0.570
ECA4366
Similar to Salmonella typhi hypothetical protein Sty4178 SWALL:Q8Z293 (EMBL:AL627281) (523 aa) fasta scores: E(): 3.7e-67, 44.09% id in 381 aa, and to Escherichia coli hypothetical protein yhjs or b3536 SWALL:YHJS_ECOLI (SWALL:P37657) (523 aa) fasta scores: E(): 1.6e-66, 44.97% id in 378 aa.
  
     0.549
ppa
Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
      
 0.530
ECA2215
Putative short-chain dehydrogenase; Similar to Vibrio vulnificus dehydrogenase vv12935 SWALL:AAO11267 (EMBL:AE016806) (241 aa) fasta scores: E(): 2.9e-42, 50.84% id in 236 aa, and to Pseudomonas putida oxidoreductase, short-chain dehydrogenase/reductase family pp2737 SWALL:AAN68345 (EMBL:AE016784) (250 aa) fasta scores: E(): 3.7e-28, 42.21% id in 244 aa.
 
     0.525
ECA0969
Similar to Yersinia pestis putative tetr-family regulatory protein ypo3840 or y0390 SWALL:AAM83979 (EMBL:AJ414159) (228 aa) fasta scores: E(): 1.4e-33, 71.36% id in 213 aa, and to Rhizobium loti transcriptional regulator mll3386 SWALL:Q98GC7 (EMBL:AP003001) (219 aa) fasta scores: E(): 3.2e-30, 48.66% id in 187 aa.
  
     0.512
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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