STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA2226Similar to Escherichia coli methyl-accepting chemotaxis protein II Tar or CheM or b1886 SWALL:MCP2_ECOLI (SWALL:P07017) (553 aa) fasta scores: E(): 1.4e-48, 50.98% id in 355 aa, and to Ralstonia solanacearum putative methyl-accepting chemotaxis transmembrane protein rsc0606 or rs06104 SWALL:Q8Y1T3 (EMBL:AL646060) (617 aa) fasta scores: E(): 1.2e-54, 39.73% id in 594 aa. (611 aa)    
Predicted Functional Partners:
cheA
Chemotaxis protein; Similar to Escherichia coli chemotaxis protein CheA or b1888 SWALL:CHEA_ECOLI (SWALL:P07363) (654 aa) fasta scores: E(): 2.8e-114, 74.4% id in 668 aa.
 
 0.976
cheW
Chemotaxis protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri chemotaxis protein CheW or b1887 or c2302 or z2941 or ecs2597 or sf1936 SWALL:CHEW_ECOLI (SWALL:P07365) (167 aa) fasta scores: E(): 3.6e-50, 86.33% id in 161 aa.
 
 
 0.958
cheR
Chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
 
 
 0.949
cheB
Protein-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.941
ECA1568
Putative chemotaxis signal transduction protein; Similar to Vibrio fischeri CheV SWALL:AAL86625 (EMBL:AY079167) (306 aa) fasta scores: E(): 1.6e-26, 34.36% id in 323 aa, and to Salmonella typhimurium putative chemotaxis signal transduction protein stm2314 SWALL:Q8ZNE6 (EMBL:AE008803) (333 aa) fasta scores: E(): 8.2e-81, 70.44% id in 318 aa.
 
 0.859
cheY
Chemotaxis protein; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri chemotaxis protein CheY or b1882 or z2936 or ecs2592 or sf1931 SWALL:CHEY_ECOLI (SWALL:P06143) (128 aa) fasta scores: E(): 6.1e-41, 91.4% id in 128 aa.
 
 0.734
ECA2225A
Hypothetical protein; No significant database matches.
       0.727
arcB
Similar to Escherichia coli, and Shigella flexneri aerobic respiration control sensor protein ArcB or b3210 or sf3250 SWALL:ARCB_ECOLI (SWALL:P22763) (778 aa) fasta scores: E(): 8.6e-180, 75.88% id in 788 aa, and to Yersinia pestis aerobic respiration control sensor/response regulatory protein ArcB SWALL:Q8ZB69 (EMBL:AJ414157) (778 aa) fasta scores: E(): 3.6e-190, 80.71% id in 788 aa.
  
 
 0.620
rpfA
Two-component sensor kinase and response regulator; Similar to Pectobacterium carotovorum subsp. carotovorum sensor/regulator protein RpfA SWALL:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 92.88% id in 928 aa, and to Pectobacterium carotovorum subsp. carotovorum sensory kinase ExpS SWALL:O32556 (EMBL:Y13670) (928 aa) fasta scores: E(): 0, 95.36% id in 928 aa.
 
 
 0.585
fliM
Flagellar motor switch protein; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
  
  
 0.542
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.