STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA2236Similar to Pseudomonas aeruginosa hypothetical protein Pa2120 SWALL:Q9I1Z5 (EMBL:AE004639) (142 aa) fasta scores: E(): 7.7e-15, 43.41% id in 129 aa, and to Ralstonia solanacearum hypothetical protein rsp0317 or rs05451 SWALL:Q8XT00 (EMBL:AL646078) (147 aa) fasta scores: E(): 6.5e-12, 36.5% id in 126 aa. (147 aa)    
Predicted Functional Partners:
ECA2233
Probable hydrolase; Similar to uncultured bacterium esterase SWALL:Q9KIU0 (EMBL:AF223648) (438 aa) fasta scores: E(): 5.5e-34, 42.48% id in 306 aa, and to Clostridium acetobutylicum carboxyl esterase, a/b hydrolase cap0097 SWALL:Q97TK4 (EMBL:AE001438) (299 aa) fasta scores: E(): 1e-42, 42.12% id in 292 aa.
  
     0.645
ECA2235A
Putative short-chain dehydrogenase (partial); Similar to the C-terminal regions of several including Agrobacterium tumefaciens short-chain dehydrogenase atu5444 or agr_pat_651 SWALL:Q8UJN2 (EMBL:AE008965) (287 aa) fasta scores: E(): 7.5e-08, 50% id in 60 aa, and to Pseudomonas sp. putative short chain dehydrogenase orf65 SWALL:Q936Z5 (EMBL:U66917) (147 aa) fasta scores: E(): 3.2e-07, 50% id in 60 aa.
 
     0.591
ECA2235
Putative transcriptional regulator; Similar to Pseudomonas putida conserved hypothetical protein pp2987 SWALL:AAN68595 (EMBL:AE016785) (187 aa) fasta scores: E(): 2.1e-33, 70.24% id in 121 aa, and to Rhizobium loti hypothetical protein Mll2592 SWALL:Q98I32 (EMBL:AP003000) (182 aa) fasta scores: E(): 6.4e-17, 49.56% id in 115 aa.
 
     0.474
ECA2071
Putative cytochrome P450; Similar to Mycobacterium leprae putative cytochrome P450 ml2088 SWALL:Q9CBE7 (EMBL:AL583924) (434 aa) fasta scores: E(): 7.1e-22, 26.3% id in 422 aa, and to Bacillus subtilis putative cytochrome P450 YjiB SWALL:YJIB_BACSU (SWALL:O34374) (396 aa) fasta scores: E(): 1.8e-20, 27.11% id in 343 aa.
  
    0.471
fabR
TetR-family trancriptional regulator; Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.
  
     0.456
flxA
Conserved hypothetical protein; Similar to Escherichia coli protein FlxA or b1566 SWALL:FLXA_ECOLI (SWALL:P77609) (110 aa) fasta scores: E(): 0.0012, 34.74% id in 118 aa, and to Shigella flexneri orf, conserved hypothetical protein sf2463 SWALL:AAN43970 (EMBL:AE015262) (113 aa) fasta scores: E(): 3.1e-06, 43.39% id in 106 aa.
       0.455
nahO
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
  
     0.433
ECA2295
AraC-family transcriptional regulator; Similar to Pseudomonas sp. 61-3 PhbR SWALL:Q9Z3Y6 (EMBL:AB014757) (379 aa) fasta scores: E(): 2.4e-41, 35.01% id in 337 aa, and to Azotobacter sp. FA8 PhaR protein PhaR SWALL:Q8KRE8 (EMBL:AJ496234) (369 aa) fasta scores: E(): 7.9e-33, 31.36% id in 338 aa.
  
     0.427
ECA0371
Putative transcriptional regulator; Similar to Pseudomonas putida conserved hypothetical protein pp0502 SWALL:AAN66130 (EMBL:AE016775) (147 aa) fasta scores: E(): 8e-26, 55.14% id in 136 aa. Note that there are no significant database matches to enterobacterial species.
 
     0.418
nahM
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
  
     0.401
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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