STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA2252Similar to Escherichia coli probable oxidoreductase ydfg or b1539 SWALL:YDFG_ECOLI (SWALL:P39831) (248 aa) fasta scores: E(): 2.3e-73, 78.62% id in 248 aa, and to Salmonella typhimurium, and Salmonella typhi hypothetical oxidoreductase ydfg or stm1511 or sty1550 SWALL:YDFG_SALTY (SWALL:P40864) (248 aa) fasta scores: E(): 2.6e-73, 77.73% id in 247 aa; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (249 aa)    
Predicted Functional Partners:
ECA2694
Putative polyketide synthetase; Similar to Amycolatopsis mediterranei peptide synthetase BpsD SWALL:Q939Y2 (EMBL:Y16952) (581 aa) fasta scores: E(): 2e-44, 32.34% id in 575 aa, and to Myxococcus xanthus Ta1 SWALL:Q9Z5F4 (EMBL:AJ006977) (2393 aa) fasta scores: E(): 4e-51, 32.97% id in 552 aa.
  
 0.923
tdh
L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.
    
 0.902
kbl
2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
    
  0.901
ECA2251
Hypothetical protein; No significant database matches.
       0.773
ECA2250
Putative aminotransferase; Similar to Xanthomonas campestris histidinol-phosphate aminotransferase hisc or xcc3275 SWALL:Q8P5R1 (EMBL:AE012444) (399 aa) fasta scores: E(): 2.9e-27, 31.33% id in 367 aa, and to Pseudomonas fluorescens putative aminotransferase qbsB SWALL:AAL65284 (EMBL:AY072690) (363 aa) fasta scores: E(): 1.1e-26, 32.2% id in 354 aa.
       0.718
gcvP
Putative glycine cleavage system P protein (glycine dehydrogenase [decarboxylating]); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
 
      0.705
ECA0705
Partial CDS. Similar to an internal region of Agrobacterium tumefaciens non-ribosomal peptide synthetase MtaD or atu3682 or agr_l_2311 SWALL:Q8U9P4 (EMBL:AE009297) (2399 aa) fasta scores: E(): 0.00074, 32.99% id in 97 aa, and to Anabaena sp. peptide synthetase all2648 SWALL:Q8YTR5 (EMBL:AP003590) (2588 aa) fasta scores: E(): 0.0032, 34.4% id in 93 aa.
  
  
 0.684
ECA0483
Similar to Tolypothrix sp. PCC 7601/1 peptide synthetase TpsA SWALL:Q93IL7 (EMBL:AJ318786) (930 aa) fasta scores: E(): 4.5e-41, 30.3% id in 561 aa, and to Pseudomonas syringae syringomycin biosynthesis enzyme 1 SyrB1 SWALL:Q52400 (EMBL:U25130) (614 aa) fasta scores: E(): 1e-40, 32.3% id in 517 aa; Belongs to the ATP-dependent AMP-binding enzyme family.
     0.668
cfa6
Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa.
  
 0.620
ECA2253
Putative exported protein; Similar to Yersinia pseudotuberculosis hypothetical 14.2 kDa protein orf9 SWALL:Q93AP0 (EMBL:AF418982) (124 aa) fasta scores: E(): 8.4e-19, 45.52% id in 123 aa, and to Salmonella typhimurium, and Salmonella typhi putative periplasmic protein ynfb or stm1503 or sty1560 SWALL:Q8XEU2 (EMBL:AE008765) (113 aa) fasta scores: E(): 3.1e-18, 52.52% id in 99 aa; Belongs to the UPF0482 family.
  
    0.438
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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