Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
manASimilar to Escherichia coli mannose-6-phosphate isomerase ManA or Pmi or b1613 SWALL:MANA_ECOLI (SWALL:P00946) (391 aa) fasta scores: E(): 1e-110, 71.28% id in 390 aa. (390 aa)    
Predicted Functional Partners:
rfbK
Phosphomannomutase; Similar to Escherichia coli phosphomannomutase ManB or RfbK or RfbK2 SWALL:RFK9_ECOLI (SWALL:P37755) (456 aa) fasta scores: E(): 8.5e-137, 74.34% id in 456 aa.
  
 
 0.988
pgi
Glucose-6-phosphate isomerase; Similar to Escherichia coli, and Escherichia coli O157:H7 glucose-6-phosphate isomerase Pgi or b4025 or z5623 or ecs5008 SWALL:G6PI_ECOLI (SWALL:P11537) (549 aa) fasta scores: E(): 1.4e-193, 86.86% id in 548 aa.
 
 
 0.981
manX
PTS system, mannose-specific IIab component; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri PTS system, mannose-specific iiab component ManX or PtsL or GptB or b1817 or c2223 or z2860 or ecs2527 or sf1411 SWALL:PTNA_ECOLI (SWALL:P08186) (322 aa) fasta scores: E(): 5.5e-80, 74.84% id in 322 aa.
    
 0.974
glmS
Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.955
nagB
Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
     
 0.954
mtlD
Similar to Escherichia coli mannitol-1-phosphate 5-dehydrogenase MtlD or b3600 SWALL:MTLD_ECOLI (SWALL:P09424) (382 aa) fasta scores: E(): 5.7e-108, 77.48% id in 382 aa.
 
  
 0.953
ECA1107
Similar to Escherichia coli hypothetical protein YajF or b0394 SWALL:YAJF_ECOLI (SWALL:P23917) (302 aa) fasta scores: E(): 5e-91, 75.74% id in 301 aa, and to Salmonella typhimurium putative sugar kinase/putative transcriptional regulator YajF or stm0393 SWALL:Q8ZRE5 (EMBL:AE008713) (302 aa) fasta scores: E(): 6.6e-91, 75.66% id in 300 aa.
  
 
 0.952
manZ
PTS system, mannose-specific iid component; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 PTS system, mannose-specific IId component ManZ or PtsM or GptB or b1819 or c2226 or z2862 or ecs2529 SWALL:PTND_ECOLI (SWALL:P08188) (286 aa) fasta scores: E(): 4.9e-91, 83.45% id in 278 aa.
    
 0.952
manY
PTS system, mannose-specific IIc component; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri PTS system, mannose-specific IIc component ManY or PtsP or Pel or b1818 or c2224 or z2861 or ecs2528 or sf1410 SWALL:PTNC_ECOLI (SWALL:P08187) (266 aa) fasta scores: E(): 1e-78, 87.21% id in 266 aa.
    
  0.950
scrK
Fructokinase; Similar to Escherichia coli fructokinase CscK SWALL:SCRK_ECOLI (SWALL:P40713) (307 aa) fasta scores: E(): 4.5e-67, 60.39% id in 303 aa, and to Erwinia amylovora fructokinase ScrK SWALL:Q9F4A1 (EMBL:AJ250722) (308 aa) fasta scores: E(): 1.6e-65, 60.06% id in 303 aa; Belongs to the carbohydrate kinase PfkB family.
    
 0.949
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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