Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECA2264Putative exported protein; Similar to Escherichia coli O6 hypothetical protein ydga or c2006 SWALL:AAN80466 (EMBL:AE016761) (502 aa) fasta scores: E(): 3.5e-65, 38.67% id in 512 aa, and to Shigella flexneri orf, conserved hypothetical protein ydga or sf1637 SWALL:AAN43220 (EMBL:AE015185) (502 aa) fasta scores: E(): 3.5e-65, 38.67% id in 512 aa. (516 aa)    
Predicted Functional Partners:
rof
Modulator of rho-dependent transcription termination; Similar to Escherichia coli, and Shigella flexneri Rof protein or b0189 or sf0179 SWALL:ROF_ECOLI (SWALL:P52098) (84 aa) fasta scores: E(): 3.4e-22, 70.23% id in 84 aa, and to Salmonella typhimurium modulator of rho-dependent transcription termination Rof or stm0237 SWALL:Q8ZRN4 (EMBL:AE008706) (86 aa) fasta scores: E(): 2.9e-20, 66.27% id in 86 aa.
  
     0.772
rcsD
Putative two-component system sensor kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
  
     0.771
asmA
Putative outer membrane assembly protein; Similar to Escherichia coli protein AsmA precursor AsmA or b2064 SWALL:ASMA_ECOLI (SWALL:P28249) (617 aa) fasta scores: E(): 2.2e-107, 47.74% id in 620 aa.
  
     0.770
ECA2003
Putative exported protein; Similar to Yersinia pestis hypothetical protein y2005 SWALL:AAM85571 (EMBL:AE013803) (898 aa) fasta scores: E(): 1e-188, 52.6% id in 865 aa, and to Escherichia coli O6 hypothetical protein ydbh or c1828 SWALL:AAN80292 (EMBL:AE016760) (879 aa) fasta scores: E(): 2.9e-148, 44.01% id in 861 aa.
  
     0.769
ftsN
Cell division protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.
  
     0.765
ECA1447
Putative exported protein; Similar to Escherichia coli hypothetical protein ymcb precursor ymcb or b0985 SWALL:YMCB_ECOLI (SWALL:P75883) (248 aa) fasta scores: E(): 3.6e-08, 31% id in 258 aa, and to Shigella flexneri orf, conserved hypothetical protein ymcb or sf0987 SWALL:AAN42615 (EMBL:AE015127) (248 aa) fasta scores: E(): 3.6e-08, 32.04% id in 259 aa.
  
     0.763
holD
DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.
  
     0.761
lpoB
Putative lipoprotein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b). Belongs to the LpoB family.
  
  
 0.760
ECA2468
Putative exported protein; Similar to Salmonella typhimurium putative outer membrane protein ycfr or stm1214 SWALL:Q8ZQ03 (EMBL:AE008753) (85 aa) fasta scores: E(): 2.6e-06, 48.23% id in 85 aa, and to Escherichia coli, Escherichia coli O6, and Shigella flexneri hypothetical protein ybij precursor ybij or b0802 or c0886 or sf0752 SWALL:YBIJ_ECOLI (SWALL:P41038) (86 aa) fasta scores: E(): 1.3e-05, 52.32% id in 86 aa.
  
     0.758
ECA2009
Putative exported protease; Similar to Shigella flexneri orf, conserved hypothetical protein sf1619 SWALL:AAN43202 (EMBL:AE015183) (273 aa) fasta scores: E(): 1.1e-59, 57.35% id in 272 aa, and to Escherichia coli putative protease ydgd precursor ydgd or b1598 SWALL:YDGD_ECOLI (SWALL:P76176) (273 aa) fasta scores: E(): 1.8e-59, 57.35% id in 272 aa; Belongs to the peptidase S1B family.
  
     0.752
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.