STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
addSimilar to Escherichia coli adenosine deaminase Add or b1623 SWALL:ADD_ECOLI (SWALL:P22333) (333 aa) fasta scores: E(): 2.2e-89, 71.77% id in 333 aa; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. (337 aa)    
Predicted Functional Partners:
ushA
Similar to Escherichia coli protein UshA precursor [includes: UDP-sugar hydrolase and 5'-nucleotidase] UshA or b0480 SWALL:USHA_ECOLI (SWALL:P07024) (550 aa) fasta scores: E(): 1.6e-157, 71.5% id in 551 aa; Belongs to the 5'-nucleotidase family.
 
  
 0.922
deoD
Purine nucleoside phosphorylase; Similar to Escherichia coli, and Escherichia coli O157:H7 purine nucleoside phosphorylase deoD or Pup or b4384 or z5986 or ecs5343 SWALL:DEOD_ECOLI (SWALL:P09743) (238 aa) fasta scores: E(): 2.1e-80, 89.07% id in 238 aa.
    
 0.911
ECA0053
Putative phosphodiesterase; Similar to Vibrio cholerae 2`,3`-cyclic-nucleotide 2`-phosphodiesterase, putative vc2416 SWALL:Q9KPF2 (EMBL:AE004311) (634 aa) fasta scores: E(): 9.2e-161, 66.4% id in 634 aa; Belongs to the 5'-nucleotidase family.
    
 0.908
cpdB
Similar to Escherichia coli 2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor CpdB or b4213 SWALL:CN16_ECOLI (SWALL:P08331) (647 aa) fasta scores: E(): 9.6e-198, 76.68% id in 639 aa; Belongs to the 5'-nucleotidase family.
    
 0.908
ECA4424
Similar to Rhizobium meliloti putative nucleoside hydrolase protein r00415 or smc01105 SWALL:Q92SI0 (EMBL:AL591783) (314 aa) fasta scores: E(): 6.6e-47, 46.32% id in 313 aa, and to Agrobacterium tumefaciens inosine-uridine preferring nucleoside hydrolase iunh or atu0374 or agr_c_654 SWALL:Q8UIC3 (EMBL:AE009008) (333 aa) fasta scores: E(): 4.3e-50, 49.83% id in 309 aa; Belongs to the IUNH family.
 
 
 0.908
ECA4423
Similar to Rhizobium meliloti putative nucleoside hydrolase protein r00415 or smc01105 SWALL:Q92SI0 (EMBL:AL591783) (314 aa) fasta scores: E(): 1.3e-49, 47.74% id in 310 aa, and to Agrobacterium tumefaciens inosine-uridine preferring nucleoside hydrolase IunH or atu0374 or agr_c_654 SWALL:Q8UIC3 (EMBL:AE009008) (333 aa) fasta scores: E(): 2.5e-48, 44.37% id in 311 aa; Belongs to the IUNH family.
 
 
 0.907
ECA4103
Putative hydrolase; Similar to Yersinia pestis hypothetical protein ypo0141 or y3921 SWALL:AAM87465 (EMBL:AJ414141) (226 aa) fasta scores: E(): 4.7e-69, 76.57% id in 222 aa, and to Salmonella typhi putative hydrolase yrfg or sty4300 SWALL:Q8Z212 (EMBL:AL627281) (236 aa) fasta scores: E(): 7.2e-59, 65.31% id in 222 aa.
    
 0.906
ppnP
Conserved hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
     
 0.902
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
  
  
 0.558
ECA2265
Putative membrane protein; Similar to Pseudomonas resinovorans efflux pump SWALL:BAC41699 (EMBL:AB088420) (319 aa) fasta scores: E(): 4.4e-44, 44.08% id in 313 aa, and to Pseudomonas putida transporter, bile acid/na+ symporter family pp0670 SWALL:AAN66295 (EMBL:AE016776) (317 aa) fasta scores: E(): 6.3e-48, 46.45% id in 310 aa.
       0.500
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (14%) [HD]