STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA2291Similar to Yersinia pestis putative RNA pseudouridylate synthase-family protein ypo2213 SWALL:Q8ZEG0 (EMBL:AJ414151) (318 aa) fasta scores: E(): 8.9e-95, 84.58% id in 279 aa, and to Escherichia coli hypothetical protein ycil ycil or b1269 SWALL:YCIL_ECOLI (SWALL:P37765) (291 aa) fasta scores: E(): 2e-92, 79.93% id in 294 aa; Belongs to the pseudouridine synthase RsuA family. (294 aa)    
Predicted Functional Partners:
engA
Probable GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
 
  
 0.870
cmk
Cytidylate kinase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 cytidylate kinase Cmk or MssA or b0910 or c1048 or z1256 or ecs0993 SWALL:KCY_ECOLI (SWALL:P23863) (227 aa) fasta scores: E(): 3.1e-66, 83.55% id in 225 aa.
  
 0.791
xthA
Similar to Escherichia coli exodeoxyribonuclease III XthA or Xth or b1749 SWALL:EX3_ECOLI (SWALL:P09030) (268 aa) fasta scores: E(): 1.3e-87, 76.31% id in 266 aa.
  
    0.614
ECA2292
Similar to Yersinia pestis hypothetical protein ypo2212 or y2053 SWALL:Q8ZEG1 (EMBL:AJ414151) (206 aa) fasta scores: E(): 8.9e-67, 85.36% id in 205 aa, and to Salmonella enterica subsp. enterica serovar Typhi Ty2 hypothetical protein SWALL:AAO69260 (EMBL:AE016839) (206 aa) fasta scores: E(): 4.7e-61, 77.67% id in 206 aa; Belongs to the SUA5 family.
  
  
 0.579
rlmL
Putative RNA methylase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.
  
 
 0.532
rlmN
Conserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.
 
  
 0.488
gidB
Glucose inhibited division protein B; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
 
   
 0.483
sun
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
 
  
 0.482
trmB
Putative methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
 
  
 0.477
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...]
 
     0.469
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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