STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA2292Similar to Yersinia pestis hypothetical protein ypo2212 or y2053 SWALL:Q8ZEG1 (EMBL:AJ414151) (206 aa) fasta scores: E(): 8.9e-67, 85.36% id in 205 aa, and to Salmonella enterica subsp. enterica serovar Typhi Ty2 hypothetical protein SWALL:AAO69260 (EMBL:AE016839) (206 aa) fasta scores: E(): 4.7e-61, 77.67% id in 206 aa; Belongs to the SUA5 family. (206 aa)    
Predicted Functional Partners:
trpH
Putative phosphoesterase; Similar to Salmonella typhimurium protein TrpH or stm1721 SWALL:TRPH_SALTY (SWALL:O54453) (293 aa) fasta scores: E(): 1.3e-72, 68.75% id in 272 aa, and to Escherichia coli protein TrpH or b1266 SWALL:TRPH_ECOLI (SWALL:P77766) (293 aa) fasta scores: E(): 6.4e-73, 68.75% id in 272 aa.
 
    0.701
ECA2291
Similar to Yersinia pestis putative RNA pseudouridylate synthase-family protein ypo2213 SWALL:Q8ZEG0 (EMBL:AJ414151) (318 aa) fasta scores: E(): 8.9e-95, 84.58% id in 279 aa, and to Escherichia coli hypothetical protein ycil ycil or b1269 SWALL:YCIL_ECOLI (SWALL:P37765) (291 aa) fasta scores: E(): 2e-92, 79.93% id in 294 aa; Belongs to the pseudouridine synthase RsuA family.
  
  
 0.579
trmB
Putative methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
 
  
 0.517
ECA3938
Conserved hypothetical protein; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein yjee or b4168 or z5775 or ecs5144 or sf4323 SWALL:YJEE_ECOLI (SWALL:P31805) (153 aa) fasta scores: E(): 3.4e-43, 73.02% id in 152 aa, and to Salmonella typhi hypothetical protein yjee or sty4714 SWALL:Q8Z189 (EMBL:AL627283) (153 aa) fasta scores: E(): 1.3e-42, 71.71% id in 152 aa.
 
   
 0.484
ECA2374
Similar to Yersinia pestis hypothetical protein Ypo2072 SWALL:Q8ZET1 (EMBL:AJ414151) (232 aa) fasta scores: E(): 1.3e-62, 72.84% id in 232 aa, and to Escherichia coli hypothetical protease yeaz yeaz or b1807 SWALL:YEAZ_ECOLI (SWALL:P76256) (231 aa) fasta scores: E(): 2.8e-59, 69.13% id in 230 aa.
 
   
 0.482
sbcC
Exonuclease; Similar to Escherichia coli exonuclease SbcC or RmuA or b0397 SWALL:SBCC_ECOLI (SWALL:P13458) (1048 aa) fasta scores: E(): 2.3e-52, 44.02% id in 1231 aa, and to Yersinia pestis ATP-dependent dsdna exonuclease SbcC or y0976 SWALL:AAM84557 (EMBL:AE013701) (1229 aa) fasta scores: E(): 2e-154, 50.04% id in 1233 aa.
   
   0.465
gcp
O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
  
  
 0.445
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
   
 0.438
sun
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
 
  
 0.437
ECA2294
Putative glycosyl transferase; Similar to Pseudomonas putida beta-(1-3)-glucosyl transferase, putative pp1526 SWALL:AAN67147 (EMBL:AE016779) (863 aa) fasta scores: E(): 2.2e-39, 32.08% id in 455 aa, and to Synechococcus elongatus cellulose synthase tll0007 SWALL:BAC07560 (EMBL:AP005369) (736 aa) fasta scores: E(): 2.9e-18, 26.26% id in 552 aa.
 
     0.434
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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