STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECA2292Similar to Yersinia pestis hypothetical protein ypo2212 or y2053 SWALL:Q8ZEG1 (EMBL:AJ414151) (206 aa) fasta scores: E(): 8.9e-67, 85.36% id in 205 aa, and to Salmonella enterica subsp. enterica serovar Typhi Ty2 hypothetical protein SWALL:AAO69260 (EMBL:AE016839) (206 aa) fasta scores: E(): 4.7e-61, 77.67% id in 206 aa; Belongs to the SUA5 family. (206 aa)    
Predicted Functional Partners:
trpH
Putative phosphoesterase; Similar to Salmonella typhimurium protein TrpH or stm1721 SWALL:TRPH_SALTY (SWALL:O54453) (293 aa) fasta scores: E(): 1.3e-72, 68.75% id in 272 aa, and to Escherichia coli protein TrpH or b1266 SWALL:TRPH_ECOLI (SWALL:P77766) (293 aa) fasta scores: E(): 6.4e-73, 68.75% id in 272 aa.
 
    0.735
ECA2291
Similar to Yersinia pestis putative RNA pseudouridylate synthase-family protein ypo2213 SWALL:Q8ZEG0 (EMBL:AJ414151) (318 aa) fasta scores: E(): 8.9e-95, 84.58% id in 279 aa, and to Escherichia coli hypothetical protein ycil ycil or b1269 SWALL:YCIL_ECOLI (SWALL:P37765) (291 aa) fasta scores: E(): 2e-92, 79.93% id in 294 aa; Belongs to the pseudouridine synthase RsuA family.
  
  
 0.625
ECA2374
Similar to Yersinia pestis hypothetical protein Ypo2072 SWALL:Q8ZET1 (EMBL:AJ414151) (232 aa) fasta scores: E(): 1.3e-62, 72.84% id in 232 aa, and to Escherichia coli hypothetical protease yeaz yeaz or b1807 SWALL:YEAZ_ECOLI (SWALL:P76256) (231 aa) fasta scores: E(): 2.8e-59, 69.13% id in 230 aa.
 
   
 0.618
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
 
  
 0.540
rpoZ
DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
    0.517
trmD
tRNA(guanine-N1)methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
      
 0.503
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
  
  
 0.492
gcp
O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
  
 
 0.487
trmB
Putative methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
 
  
 0.473
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
     0.467
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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