Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
trpHPutative phosphoesterase; Similar to Salmonella typhimurium protein TrpH or stm1721 SWALL:TRPH_SALTY (SWALL:O54453) (293 aa) fasta scores: E(): 1.3e-72, 68.75% id in 272 aa, and to Escherichia coli protein TrpH or b1266 SWALL:TRPH_ECOLI (SWALL:P77766) (293 aa) fasta scores: E(): 6.4e-73, 68.75% id in 272 aa. (294 aa)    
Predicted Functional Partners:
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
    
 0.894
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
    
  0.844
ECA2292
Similar to Yersinia pestis hypothetical protein ypo2212 or y2053 SWALL:Q8ZEG1 (EMBL:AJ414151) (206 aa) fasta scores: E(): 8.9e-67, 85.36% id in 205 aa, and to Salmonella enterica subsp. enterica serovar Typhi Ty2 hypothetical protein SWALL:AAO69260 (EMBL:AE016839) (206 aa) fasta scores: E(): 4.7e-61, 77.67% id in 206 aa; Belongs to the SUA5 family.
 
    0.735
ECA2294
Putative glycosyl transferase; Similar to Pseudomonas putida beta-(1-3)-glucosyl transferase, putative pp1526 SWALL:AAN67147 (EMBL:AE016779) (863 aa) fasta scores: E(): 2.2e-39, 32.08% id in 455 aa, and to Synechococcus elongatus cellulose synthase tll0007 SWALL:BAC07560 (EMBL:AP005369) (736 aa) fasta scores: E(): 2.9e-18, 26.26% id in 552 aa.
       0.516
ECA2291
Similar to Yersinia pestis putative RNA pseudouridylate synthase-family protein ypo2213 SWALL:Q8ZEG0 (EMBL:AJ414151) (318 aa) fasta scores: E(): 8.9e-95, 84.58% id in 279 aa, and to Escherichia coli hypothetical protein ycil ycil or b1269 SWALL:YCIL_ECOLI (SWALL:P37765) (291 aa) fasta scores: E(): 2e-92, 79.93% id in 294 aa; Belongs to the pseudouridine synthase RsuA family.
       0.439
fruA
Similar to Escherichia coli pts system, fructose-specific IIbc component FruA or PtsF or b2167 SWALL:PTFB_ECOLI (SWALL:P20966) (563 aa) fasta scores: E(): 1.4e-146, 75.13% id in 567 aa.
     
  0.437
argA
Amino-acid acetyltransferase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 amino-acid acetyltransferase ArgA or b2818 or c3412 or z4135 or ecs3675 SWALL:ARGA_ECOLI (SWALL:P08205) (443 aa) fasta scores: E(): 1.7e-149, 85.26% id in 441 aa, and to Yersinia pestis amino-acid acetyltransferase ArgA or ypo1022 or y3162 SWALL:Q8ZH86 (EMBL:AJ414146) (441 aa) fasta scores: E(): 1.5e-152, 88.43% id in 441 aa; Belongs to the acetyltransferase family. ArgA subfamily.
  
   
 0.418
yacG
Conserved hypothetical protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
  
     0.403
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: medium (60%) [HD]