STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpCN-(5'-phosphoribosyl)anthranilate isomerase; Similar to Escherichia coli tryptophan biosynthesis protein TrpC [includes: indole-3-glycerol phosphate synthase trpc or b1262 SWALL:TRPC_ECOLI (SWALL:P00909) (452 aa) fasta scores: E(): 1.6e-121, 69.93% id in 449 aa. (455 aa)    
Predicted Functional Partners:
trpG
Similar to Serratia marcescens anthranilate synthase component II TrpG SWALL:TRPG_SERMA (SWALL:P00900) (192 aa) fasta scores: E(): 6.3e-60, 85.34% id in 191 aa, and to Yersinia pestis anthranilate synthase component II TrpG or ypo2207 or y2050.1 SWALL:Q8ZEG6 (EMBL:AJ414151) (192 aa) fasta scores: E(): 5.4e-62, 84.89% id in 192 aa.
  
 0.999
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 0.999
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
 0.999
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
 
 0.999
trpE
Similar to Escherichia coli anthranilate synthase component I TrpE or b1264 SWALL:TRPE_ECOLI (SWALL:P00895) (520 aa) fasta scores: E(): 2.8e-154, 77.5% id in 520 aa.
 
 0.995
ECA4066
Para-aminobenzoate synthase, glutamine amidotransferase component II.
  
 0.991
ehpC
Putative phenazine antibiotic biosynthesis protein; Similar to Pseudomonas aeruginosa PhzE and pa4214 SWALL:O33410 (EMBL:AF005404) (627 aa) fasta scores: E(): 1.2e-105, 45.65% id in 622 aa, and to Pantoea agglomerans EhpC SWALL:AAN40892 (EMBL:AF451953) (634 aa) fasta scores: E(): 6.8e-55, 37.82% id in 624 aa.
 
 
 0.986
pabB
Similar to Escherichia coli para-aminobenzoate synthase component I PabB or b1812 SWALL:PABB_ECOLI (SWALL:P05041) (453 aa) fasta scores: E(): 6.5e-119, 66.51% id in 433 aa.
 
 0.971
ECA2772
Putative glycosyl transferase; Similar to Escherichia coli hypothetical protein ybib or b0800 SWALL:YBIB_ECOLI (SWALL:P30177) (320 aa) fasta scores: E(): 8.8e-82, 63.95% id in 319 aa, and to Yersinia pestis putative glycosyl transferase ypo2522 or y1665 SWALL:Q8ZDN8 (EMBL:AJ414152) (319 aa) fasta scores: E(): 3.3e-79, 66.03% id in 318 aa.
 
  
 0.765
hisI
Similar to Escherichia coli histidine biosynthesis bifunctional protein HisIE [includes: phosphoribosyl-AMP cyclohydrolase and phosphoribosyl-ATP pyrophosphatase HisI or hisie or b2026 SWALL:HIS2_ECOLI (SWALL:P06989) (203 aa) fasta scores: E(): 2e-64, 80.09% id in 201 aa; In the N-terminal section; belongs to the PRA-CH family.
 
  
 0.721
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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