STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA2314Putative acyl-CoA thioester hydrolase; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri putative acyl-CoA thioester hydrolase ycia or b1253 or c1719 or sf1256 SWALL:YCIA_ECOLI (SWALL:P04379) (132 aa) fasta scores: E(): 1.2e-41, 80% id in 130 aa, and to Yersinia pestis putative acyl-CoA thioester hydrolase ypo2195 or y2039 SWALL:Q8ZEH6 (EMBL:AJ414151) (149 aa) fasta scores: E(): 1.5e-44, 86.15% id in 130 aa. (140 aa)    
Predicted Functional Partners:
fadB
Fatty oxidation complex alpha subunit [includes: enoyl-CoA hydratase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
  
 0.812
fadJ
Putative fatty acid oxidation complex alpha subunit; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.812
ispZ
Intracellular septation protein; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.
       0.758
fabI
Enoyl-[acyl-carrier-protein] reductase [NADH]; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri enoyl-[acyl-carrier-protein] reductase [NADH] FabI or EnvM or b1288 or z2512 or ecs1861 or sf1293 SWALL:FABI_ECOLI (SWALL:P29132) (261 aa) fasta scores: E(): 1.6e-84, 86.97% id in 261 aa.
  
  
 0.547
cfa6
Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa.
  
 
 0.545
ECA4463
Putative membrane protein; Similar to Escherichia coli, and Escherichia coli O6 hypothetical protein yiee or b3712 or c4635 SWALL:YIEE_ECOLI (SWALL:P31464) (253 aa) fasta scores: E(): 1.6e-25, 34.81% id in 247 aa, and to Salmonella typhimurium, and Salmonella typhi putative cytoplasmic protein yiee or stm3849 or sty3934 SWALL:Q8XF90 (EMBL:AE008879) (251 aa) fasta scores: E(): 6.4e-24, 33.33% id in 237 aa.
   
    0.472
ECA1369
Putative thioesterase; Similar to Yersinia pestis hypothetical protein ypo1120 or y3059 SWALL:Q8ZGZ5 (EMBL:AJ414146) (133 aa) fasta scores: E(): 5e-46, 87.21% id in 133 aa, and to Erwinia chrysanthemi YbgC protein SWALL:Q937K7 (EMBL:AJ297885) (134 aa) fasta scores: E(): 7.4e-45, 82.83% id in 134 aa.
  
 
 0.468
ECA1154
Putative thioesterase; Similar to Yersinia pestis hypothetical protein Ypo3151 ypo3151 SWALL:Q8ZC71 (EMBL:AJ414155) (135 aa) fasta scores: E(): 1.5e-32, 65.38% id in 130 aa, and to Yersinia pestis hypothetical protein y1033 SWALL:AAM84614 (EMBL:AE013707) (141 aa) fasta scores: E(): 1.5e-32, 65.38% id in 130 aa.
  
 
 0.465
fabA
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
  
  
 0.454
fadE
Similar to Escherichia coli acyl-coenzyme A dehydrogenase FadE or b0221 SWALL:FADE_ECOLI (SWALL:Q47146) (814 aa) fasta scores: E(): 0, 77.66% id in 815 aa.
  
 
 0.426
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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