STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECA2317Similar to Escherichia coli methyl-accepting chemotaxis protein I Tsr or CheD or b4355 SWALL:MCP1_ECOLI (SWALL:P02942) (551 aa) fasta scores: E(): 2.1e-47, 31.81% id in 528 aa, and to Yersinia pestis putative methyl-accepting chemotaxis protein y3190 SWALL:AAM86740 (EMBL:AE013920) (566 aa) fasta scores: E(): 8e-81, 47.86% id in 516 aa. (598 aa)    
Predicted Functional Partners:
cheA
Chemotaxis protein; Similar to Escherichia coli chemotaxis protein CheA or b1888 SWALL:CHEA_ECOLI (SWALL:P07363) (654 aa) fasta scores: E(): 2.8e-114, 74.4% id in 668 aa.
 
 0.993
cheW
Chemotaxis protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri chemotaxis protein CheW or b1887 or c2302 or z2941 or ecs2597 or sf1936 SWALL:CHEW_ECOLI (SWALL:P07365) (167 aa) fasta scores: E(): 3.6e-50, 86.33% id in 161 aa.
 
 0.992
cheR
Chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
 
 0.990
cheB
Protein-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.990
ECA1568
Putative chemotaxis signal transduction protein; Similar to Vibrio fischeri CheV SWALL:AAL86625 (EMBL:AY079167) (306 aa) fasta scores: E(): 1.6e-26, 34.36% id in 323 aa, and to Salmonella typhimurium putative chemotaxis signal transduction protein stm2314 SWALL:Q8ZNE6 (EMBL:AE008803) (333 aa) fasta scores: E(): 8.2e-81, 70.44% id in 318 aa.
 
 0.987
ECA2316
Conserved hypothetical protein; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri protein ycii or b1251 or c1716 or sf1254 SWALL:YCII_ECOLI (SWALL:P31070) (98 aa) fasta scores: E(): 7.2e-27, 75.51% id in 98 aa, and to Salmonella typhimurium, and Salmonella typhi putative cytoplasmic protein ycii or stm1738 or sty1313 SWALL:Q8XH04 (EMBL:AE008777) (98 aa) fasta scores: E(): 4.4e-26, 72.44% id in 98 aa.
       0.768
arcB
Similar to Escherichia coli, and Shigella flexneri aerobic respiration control sensor protein ArcB or b3210 or sf3250 SWALL:ARCB_ECOLI (SWALL:P22763) (778 aa) fasta scores: E(): 8.6e-180, 75.88% id in 788 aa, and to Yersinia pestis aerobic respiration control sensor/response regulatory protein ArcB SWALL:Q8ZB69 (EMBL:AJ414157) (778 aa) fasta scores: E(): 3.6e-190, 80.71% id in 788 aa.
  
 0.743
rpfA
Two-component sensor kinase and response regulator; Similar to Pectobacterium carotovorum subsp. carotovorum sensor/regulator protein RpfA SWALL:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 92.88% id in 928 aa, and to Pectobacterium carotovorum subsp. carotovorum sensory kinase ExpS SWALL:O32556 (EMBL:Y13670) (928 aa) fasta scores: E(): 0, 95.36% id in 928 aa.
  
 0.690
ECA3886
Putative membrane protein; Similar to the C-terminal region of many including Pseudomonas aeruginosa hypothetical protein Pa2870 SWALL:Q9HZX6 (EMBL:AE004713) (525 aa) fasta scores: E(): 1.9e-17, 39.39% id in 165 aa, and to Shewanella oneidensis ggdef domain protein so4457 SWALL:AAN57422 (EMBL:AE015878) (485 aa) fasta scores: E(): 2.1e-17, 39.03% id in 187 aa.
  
 0.556
tonB
TonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
       0.449
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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