STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
adhEAldehyde-alcohol dehydrogenase; Similar to Escherichia coli, and Escherichia coli O157:H7 aldehyde-alcohol dehydrogenase [includes: alcohol dehydrogenase, acetaldehyde dehydrogenase, and pyruvate-formate-lyase deactivase AdhE or Ana or b1241 or z2016 or ecs1741 SWALL:ADHE_ECOLI (SWALL:P17547) (890 aa) fasta scores: E(): 0, 89.1% id in 890 aa; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (891 aa)    
Predicted Functional Partners:
pflB
Similar to Escherichia coli formate acetyltransferase 1 PflB or Pfl or b0903 SWALL:PFLB_ECOLI (SWALL:P09373) (759 aa) fasta scores: E(): 0, 91.3% id in 759 aa.
 
 
 0.983
adhC
Similar to Escherichia coli alcohol dehydrogenase class III AdhC or b0356 SWALL:ADH3_ECOLI (SWALL:P25437) (369 aa) fasta scores: E(): 1.7e-102, 70.46% id in 369 aa, and to Yersinia pestis alcohol dehydrogenase class III, formaldehyde dehydrogenase adhc or y2667 SWALL:AAM86220 (EMBL:AE013869) (379 aa) fasta scores: E(): 2.3e-130, 91.93% id in 372 aa; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
  
 0.981
ECA3198
Putative zinc-binding dehydrogenase; Similar to Escherichia coli hypothetical zinc-type alcohol dehydrogenase-like protein yjgb or b4269 SWALL:YJGB_ECOLI (SWALL:P27250) (339 aa) fasta scores: E(): 2.9e-112, 83.18% id in 339 aa, and to Salmonella typhimurium putative alcohol dehydrogenase yjgb or stm4486 SWALL:Q8ZK20 (EMBL:AE008910) (339 aa) fasta scores: E(): 6.8e-112, 83.48% id in 339 aa.
  
 0.976
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.971
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
  
 0.969
atoA
Similar to Escherichia coli acetate CoA-transferase beta subunit AtoA or b2222 SWALL:ATOA_ECOLI (SWALL:P76459) (216 aa) fasta scores: E(): 1.4e-54, 70.33% id in 209 aa, and to Clostridium acetobutylicum butyrate-acetoacetate CoA-transferase subunit B CtfB or cap0164 SWALL:CTFB_CLOAB (SWALL:P23673) (221 aa) fasta scores: E(): 2.6e-44, 57.2% id in 215 aa.
  
 0.949
atoD
Similar to Escherichia coli acetate CoA-transferase alpha subunit AtoD or b2221 SWALL:ATOD_ECOLI (SWALL:P76458) (220 aa) fasta scores: E(): 3.9e-48, 61.46% id in 218 aa.
  
 
 0.946
nifJ
Similar to Klebsiella pneumoniae pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_KLEPN (SWALL:P03833) (1171 aa) fasta scores: E(): 0, 78.27% id in 1169 aa, and to Enterobacter agglomerans pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_ENTAG (SWALL:P19543) (1173 aa) fasta scores: E(): 0, 73.34% id in 1178 aa. Also similar to ECA0824 (NifJ) (47.377% id. in 1182 aa overlap).
  
 0.937
aceF
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.932
atoB
Similar to Clostridium acetobutylicum acetyl-CoA acetyltransferase ThlA or Thl or cac2873 SWALL:THLA_CLOAB (SWALL:P45359) (392 aa) fasta scores: E(): 9.5e-81, 59.48% id in 390 aa, and to Escherichia coli acetyl-CoA acetyltransferase AtoB or b2224 SWALL:ATOB_ECOLI (SWALL:P76461) (394 aa) fasta scores: E(): 1.2e-87, 64.01% id in 389 aa; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.926
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.