STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
expLPatatin-like phospholipase; Similar to Pectobacterium carotovorum subsp. carotovorum ExpL protein ExpL SWALL:O86196 (EMBL:AJ224437) (303 aa) fasta scores: E(): 1.2e-110, 93.37% id in 302 aa, and to Erwinia chrysanthemi RssA protein RssA SWALL:Q93KA7 (EMBL:AJ410309) (304 aa) fasta scores: E(): 3.1e-84, 72.91% id in 299 aa. (301 aa)    
Predicted Functional Partners:
expM
Response regulator; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation.
 
  
 0.757
ECA2558
Similar to Yersinia pestis putative membrane protein ypo1394 or y2778 SWALL:Q8ZGB0 (EMBL:AJ414148) (763 aa) fasta scores: E(): 7.2e-161, 50.19% id in 763 aa, and to Salmonella typhi putative competence-related protein sty0984 SWALL:Q8Z802 (EMBL:AL627268) (754 aa) fasta scores: E(): 7.2e-126, 42.52% id in 762 aa.
     
 0.664
aas
Aas bifunctional protein [includes: 2-acylglycerophosphoethanolamine acyltransferase; Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.
  
 
 0.601
ECA2332
Similar to Yersinia pestis hypothetical protein ypo2172/y2149 ypo2172 or y2149 SWALL:AAM85711 (EMBL:AJ414151) (154 aa) fasta scores: E(): 2.7e-36, 56.77% id in 155 aa, and to Shigella flexneri hypothetical protein ychj ychj or sf1233 SWALL:YCHJ_SHIFL (SWALL:P38481) (152 aa) fasta scores: E(): 6.2e-29, 47.74% id in 155 aa; Belongs to the UPF0225 family.
       0.550
tdk
Thymidine kinase; Similar to Escherichia coli thymidine kinase Tdk or b1238 SWALL:KITH_ECOLI (SWALL:P23331) (205 aa) fasta scores: E(): 1.2e-59, 78.42% id in 190 aa.
      0.484
ECA3830
Similar to Yersinia pestis putative AMP-binding enzyme-family protein ypo0537 or y3641 SWALL:Q8ZIG5 (EMBL:AJ414143) (601 aa) fasta scores: E(): 1.8e-160, 66.61% id in 599 aa, and to Vibrio vulnificus long-chain acyl-coa synthetase vv10649 SWALL:AAO09161 (EMBL:AE016799) (601 aa) fasta scores: E(): 1.8e-133, 55.31% id in 593 aa.
  
 
 0.452
ECA3886
Putative membrane protein; Similar to the C-terminal region of many including Pseudomonas aeruginosa hypothetical protein Pa2870 SWALL:Q9HZX6 (EMBL:AE004713) (525 aa) fasta scores: E(): 1.9e-17, 39.39% id in 165 aa, and to Shewanella oneidensis ggdef domain protein so4457 SWALL:AAN57422 (EMBL:AE015878) (485 aa) fasta scores: E(): 2.1e-17, 39.03% id in 187 aa.
  
  
 0.448
cfa6
Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa.
   
 0.410
pldB
Lysophospholipase L2; Similar to Escherichia coli lysophospholipase L2 PldB or b3825 SWALL:PLDB_ECOLI (SWALL:P07000) (340 aa) fasta scores: E(): 3e-78, 59.56% id in 324 aa.
  
 
 0.408
purU
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
       0.400
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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