STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pncASimilar to Escherichia coli pyrazinamidase/nicotinamidase [includes: pyrazinamidase and nicotinamidase PncA or Nam or b1768 SWALL:PNCA_ECOLI (SWALL:P21369) (213 aa) fasta scores: E(): 4.6e-48, 58.17% id in 208 aa. (215 aa)    
Predicted Functional Partners:
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
 
 
 0.991
cobB
Putative cobalamin biosynthesis/propionate catabolism protein; Similar to Salmonella typhimurium, and Salmonella typhi CobB protein CobB or stm1221 or sty1261 SWALL:COBB_SALTY (SWALL:P97013) (273 aa) fasta scores: E(): 1.4e-80, 74.81% id in 270 aa, and to Escherichia coli CobB protein CobB or b1120 SWALL:COBB_ECOLI (SWALL:P75960) (279 aa) fasta scores: E(): 3.9e-80, 74.44% id in 270 aa; Belongs to the sirtuin family. Class III subfamily.
   
 0.950
deoD
Purine nucleoside phosphorylase; Similar to Escherichia coli, and Escherichia coli O157:H7 purine nucleoside phosphorylase deoD or Pup or b4384 or z5986 or ecs5343 SWALL:DEOD_ECOLI (SWALL:P09743) (238 aa) fasta scores: E(): 2.1e-80, 89.07% id in 238 aa.
    
  0.944
ansA
Similar to Escherichia coli, and Escherichia coli O157:H7 L-asparaginase I AnsA or b1767 or z2801 or ecs2474 SWALL:ASG1_ECOLI (SWALL:P18840) (338 aa) fasta scores: E(): 7e-103, 81.12% id in 339 aa.
  
    0.858
ECA2142
Urea amidolyase; Similar to the C-terminal region of Saccharomyces cerevisiae urea amidolyase [includes: urea carboxylase and allophanate hydrolase] Dur1,2 or ybr208c or ybr1448 SWALL:DUR1_YEAST (SWALL:P32528) (1835 aa) fasta scores: E(): 0, 52.92% id in 1213 aa, and to Pseudomonas fluorescens urea amidolyase homologue uahA SWALL:Q9XAV3 (EMBL:AJ243652) (1213 aa) fasta scores: E(): 0, 51.47% id in 1224 aa.
    
 0.839
nadE
NH3-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
  
  
 0.743
ECA0705
Partial CDS. Similar to an internal region of Agrobacterium tumefaciens non-ribosomal peptide synthetase MtaD or atu3682 or agr_l_2311 SWALL:Q8U9P4 (EMBL:AE009297) (2399 aa) fasta scores: E(): 0.00074, 32.99% id in 97 aa, and to Anabaena sp. peptide synthetase all2648 SWALL:Q8YTR5 (EMBL:AP003590) (2588 aa) fasta scores: E(): 0.0032, 34.4% id in 93 aa.
  
 
 0.556
nnrE
Putative carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...]
  
    0.539
nadD
Conserved hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
    
 0.491
entB
Enterobactin synthetase component B (isochorismatase); Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri isochorismatase EntB or EntG or b0595 or z0737 or ecs0634 or sf0509 SWALL:ENTB_ECOLI (SWALL:P15048) (285 aa) fasta scores: E(): 1.1e-69, 63.63% id in 286 aa.
     
 0.488
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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