Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECA2349Conserved hypothetical protein; Similar to Salmonella enterica subsp. enterica serovar Typhi Ty2 hypothetical protein t1163 SWALL:AAO68822 (EMBL:AE016838) (428 aa) fasta scores: E(): 2.7e-140, 86.85% id in 426 aa, and to Escherichia coli hypothetical protein yeah or b1784 SWALL:YEAH_ECOLI (SWALL:P76235) (427 aa) fasta scores: E(): 3.6e-139, 87.41% id in 421 aa; Belongs to the UPF0229 family. (424 aa)    
Predicted Functional Partners:
ECA2348
Conserved hypothetical protein; Similar to Salmonella typhimurium putative ser protein kinase yeag or stm1285 SWALL:Q8ZPW2 (EMBL:AE008755) (644 aa) fasta scores: E(): 0, 94.09% id in 644 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein yeag or b1783 or c2188 or z2823 or ecs2492 SWALL:YEAG_ECOLI (SWALL:P77391) (644 aa) fasta scores: E(): 0, 94.09% id in 644 aa.
 
  
 0.997
ECA2359
Conserved hypothetical protein; Similar to Salmonella typhimurium putative cytoplasmic protein ycgb or stm1804 SWALL:Q8ZP16 (EMBL:AE008780) (510 aa) fasta scores: E(): 1.3e-185, 85.6% id in 507 aa, and to Escherichia coli hypothetical protein ycgb or b1188 SWALL:YCGB_ECOLI (SWALL:P29013) (510 aa) fasta scores: E(): 4.9e-185, 84.98% id in 506 aa.
 
  
 0.990
napD
NapAB assembly protein; Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin- arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
   
    0.550
ECA2350
Probable transport protein; Similar to Yersinia pestis putative multidrug resistance protein ypo2148 or y2173 SWALL:Q8ZEL6 (EMBL:AJ414151) (400 aa) fasta scores: E(): 3.6e-100, 68.58% id in 382 aa, and to Shewanella oneidensis drug resistance transporter, bcr/cfla family protein so4555 SWALL:AAN57516 (EMBL:AE015887) (402 aa) fasta scores: E(): 1.4e-52, 42.3% id in 390 aa.
       0.482
dkgA
Similar to Escherichia coli 2,5-diketo-D-gluconic acid reductase A DkgA or b3012 SWALL:DKGA_ECOLI (SWALL:Q46857) (275 aa) fasta scores: E(): 1e-80, 72.42% id in 272 aa. In Salmonella typhi this is a putative pseudogene but it is apparently intact here.
   
    0.454
ECA0638
Putative membrane protein; Similar to Salmonella typhimurium, and Salmonella typhi putative inner membrane protein stm3230 or sty3410 SWALL:Q8XFR8 (EMBL:AE008848) (132 aa) fasta scores: E(): 8.1e-30, 67.69% id in 130 aa, and to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein YqjE SWALL:YQJE_ECOLI (SWALL:P42618) (134 aa) fasta scores: E(): 1.3e-28, 64.39% id in 132 aa.
   
    0.450
patA
Probable aminotransferase; Catalyzes the aminotransferase reaction from putrescine to 2- oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4- aminobutanal. Also functions as a cadaverine transaminase in a a L- lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
   
    0.439
ECA3563
Conserved hypothetical protein; Similar to Xanthomonas axonopodis nonf-related protein NonF or xac3491 SWALL:Q8PGX1 (EMBL:AE011997) (226 aa) fasta scores: E(): 1.8e-58, 68.77% id in 221 aa, and to Rhizobium meliloti hypothetical protein rb0205 or smb20212 SWALL:Q92WX2 (EMBL:AL603642) (226 aa) fasta scores: E(): 3.3e-57, 66.96% id in 224 aa.
   
    0.413
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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