Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECA2367Similar to Shigella flexneri orf, conserved hypothetical protein ycgl or sf1168 SWALL:AAN42784 (EMBL:AE015143) (108 aa) fasta scores: E(): 1.3e-25, 83.52% id in 85 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 protein ycgl or b1179 or c1627 or z1941 or ecs1674 SWALL:YCGL_ECOLI (SWALL:P76003) (108 aa) fasta scores: E(): 4e-25, 82.35% id in 85 aa. (95 aa)    
Predicted Functional Partners:
hflD
Similar to Escherichia coli hypothetical protein ycfc or b1132 SWALL:YCFC_ECOLI (SWALL:P25746) (213 aa) fasta scores: E(): 2.3e-55, 71.98% id in 207 aa, and to Salmonella typhi hypothetical protein Sty1273 SWALL:Q8Z7H0 (EMBL:AL627269) (215 aa) fasta scores: E(): 7.5e-53, 68.59% id in 207 aa.
  
  
 0.741
minC
Septum site-determining protein; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.
  
  
 0.667
nfuA
Conserved hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
     0.660
ECA2342
Similar to Yersinia pestis hypothetical protein Ypo2159 SWALL:Q8ZEK6 (EMBL:AJ414151) (90 aa) fasta scores: E(): 1.4e-26, 78.88% id in 90 aa, and to Escherichia coli hypothetical protein yeac or b1777 SWALL:YEAC_ECOLI (SWALL:P76231) (90 aa) fasta scores: E(): 1.1e-22, 67.04% id in 88 aa.
  
     0.633
minE
Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
  
    0.626
zipA
Cell division protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
  
     0.618
minD
Septum site-determining protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri septum site-determining protein MinD or b1175 or c1622 or z1937 or ecs1669 or sf1162 SWALL:MIND_ECOLI (SWALL:P18197) (269 aa) fasta scores: E(): 5.8e-87, 92.93% id in 269 aa.
       0.591
sdhE
Conserved hypothetical protein; An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
  
     0.570
ECA1019
Lysine decarboxylase family protein; Similar to Salmonella typhimurium putative nucleotide binding ygdh or stm2969 SWALL:Q8ZMD2 (EMBL:AE008836) (454 aa) fasta scores: E(): 4.8e-158, 86.78% id in 454 aa, and to Yersinia pestis hypothetical protein ypo1033 or y3148 SWALL:AAM86698 (EMBL:AJ414146) (454 aa) fasta scores: E(): 2e-157, 86.12% id in 454 aa.
  
     0.570
ECA2365
Conserved hypothetical protein; Similar to Escherichia coli, and Shigella flexneri hypothetical protein ycgn or b1181 or sf1170 SWALL:AAN42786 (EMBL:AE000216) (153 aa) fasta scores: E(): 6.8e-54, 79.73% id in 148 aa, and to Yersinia pestis hypothetical protein ypo2083 or y2228 SWALL:AAM85788 (EMBL:AJ414151) (148 aa) fasta scores: E(): 7.8e-54, 80.4% id in 148 aa; Belongs to the UPF0260 family.
 
     0.554
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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