| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ECA2366 | nudL | ECA2366 | ECA2379 | Similar to Yersinia pestis putative fumarylacetoacetate hydrolase family protein ypo2082 SWALL:Q8ZES1 (EMBL:AJ414151) (218 aa) fasta scores: E(): 5.9e-73, 82.56% id in 218 aa, and to Salmonella typhimurium, and Salmonella typhi putative fumarylacetoacetate ycgm or stm1812 or sty1942 SWALL:Q8XF52 (EMBL:AE008780) (219 aa) fasta scores: E(): 3.8e-66, 75.34% id in 219 aa. | Conserved hypothetical protein; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily. | 0.458 |
| ECA2377 | nudL | ECA2377 | ECA2379 | Similar to Yersinia pestis hypothetical protein ypo1774 or y2534 SWALL:YH74_YERPE (SWALL:Q8ZFE0) (85 aa) fasta scores: E(): 1.1e-10, 53.84% id in 78 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein yoah or b1811 or c2216 or z2854 or ecs2520 SWALL:YOAH_ECOLI (SWALL:P76260) (59 aa) fasta scores: E(): 1.7e-10, 67.24% id in 58 aa; Belongs to the UPF0181 family. | Conserved hypothetical protein; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily. | 0.538 |
| ECA2377 | pabB | ECA2377 | ECA2378 | Similar to Yersinia pestis hypothetical protein ypo1774 or y2534 SWALL:YH74_YERPE (SWALL:Q8ZFE0) (85 aa) fasta scores: E(): 1.1e-10, 53.84% id in 78 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein yoah or b1811 or c2216 or z2854 or ecs2520 SWALL:YOAH_ECOLI (SWALL:P76260) (59 aa) fasta scores: E(): 1.7e-10, 67.24% id in 58 aa; Belongs to the UPF0181 family. | Similar to Escherichia coli para-aminobenzoate synthase component I PabB or b1812 SWALL:PABB_ECOLI (SWALL:P05041) (453 aa) fasta scores: E(): 6.5e-119, 66.51% id in 433 aa. | 0.534 |
| birA | cfa6 | ECA0214 | ECA0603 | Bira bifunctional protein [includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa. | 0.748 |
| birA | nnrE | ECA0214 | ECA3939 | Bira bifunctional protein [includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Putative carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...] | 0.508 |
| birA | nudL | ECA0214 | ECA2379 | Bira bifunctional protein [includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Conserved hypothetical protein; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily. | 0.553 |
| cfa6 | birA | ECA0603 | ECA0214 | Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa. | Bira bifunctional protein [includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.748 |
| cfa6 | nnrE | ECA0603 | ECA3939 | Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa. | Putative carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...] | 0.540 |
| cfa6 | nudL | ECA0603 | ECA2379 | Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa. | Conserved hypothetical protein; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily. | 0.435 |
| cfa6 | pabB | ECA0603 | ECA2378 | Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa. | Similar to Escherichia coli para-aminobenzoate synthase component I PabB or b1812 SWALL:PABB_ECOLI (SWALL:P05041) (453 aa) fasta scores: E(): 6.5e-119, 66.51% id in 433 aa. | 0.608 |
| cfa6 | rfbM | ECA0603 | ECA1438 | Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa. | Similar to Escherichia coli mannose-1-phosphate guanylyltransferase ManC or CpsB or RfbM or b2049 SWALL:MANC_ECOLI (SWALL:P24174) (478 aa) fasta scores: E(): 2.1e-114, 60.88% id in 473 aa, and to Shigella flexneri mannose-1-phosphate guanyltransferase CpsB_1 or sf2112 SWALL:AAN43651 (EMBL:AE015227) (478 aa) fasta scores: E(): 5.5e-115, 61.31% id in 473 aa; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.676 |
| nnrE | birA | ECA3939 | ECA0214 | Putative carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...] | Bira bifunctional protein [includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.508 |
| nnrE | cfa6 | ECA3939 | ECA0603 | Putative carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...] | Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa. | 0.540 |
| nnrE | nudL | ECA3939 | ECA2379 | Putative carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...] | Conserved hypothetical protein; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily. | 0.558 |
| nudC | nudL | ECA0234 | ECA2379 | Similar to Escherichia coli NADH pyrophosphatase NudC SWALL:NUDC_ECOLI (SWALL:P32664) (257 aa) fasta scores: E(): 2.2e-77, 70.42% id in 257 aa, and to Yersinia pestis NADH pyrophosphatase NudC SWALL:NUDC_YERPE (SWALL:Q8ZAQ5) (260 aa) fasta scores: E(): 1.3e-84, 75.87% id in 257 aa. | Conserved hypothetical protein; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily. | 0.541 |
| nudL | ECA2366 | ECA2379 | ECA2366 | Conserved hypothetical protein; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily. | Similar to Yersinia pestis putative fumarylacetoacetate hydrolase family protein ypo2082 SWALL:Q8ZES1 (EMBL:AJ414151) (218 aa) fasta scores: E(): 5.9e-73, 82.56% id in 218 aa, and to Salmonella typhimurium, and Salmonella typhi putative fumarylacetoacetate ycgm or stm1812 or sty1942 SWALL:Q8XF52 (EMBL:AE008780) (219 aa) fasta scores: E(): 3.8e-66, 75.34% id in 219 aa. | 0.458 |
| nudL | ECA2377 | ECA2379 | ECA2377 | Conserved hypothetical protein; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily. | Similar to Yersinia pestis hypothetical protein ypo1774 or y2534 SWALL:YH74_YERPE (SWALL:Q8ZFE0) (85 aa) fasta scores: E(): 1.1e-10, 53.84% id in 78 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein yoah or b1811 or c2216 or z2854 or ecs2520 SWALL:YOAH_ECOLI (SWALL:P76260) (59 aa) fasta scores: E(): 1.7e-10, 67.24% id in 58 aa; Belongs to the UPF0181 family. | 0.538 |
| nudL | birA | ECA2379 | ECA0214 | Conserved hypothetical protein; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily. | Bira bifunctional protein [includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.553 |
| nudL | cfa6 | ECA2379 | ECA0603 | Conserved hypothetical protein; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily. | Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa. | 0.435 |
| nudL | nnrE | ECA2379 | ECA3939 | Conserved hypothetical protein; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily. | Putative carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...] | 0.558 |
