STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ECA2410Putative sodium:dicarboxylate symporter; Similar to Yersinia pestis putative transport protein ypo1716 or y1878 SWALL:Q8ZFI7 (EMBL:AJ414150) (465 aa) fasta scores: E(): 5.1e-137, 81.68% id in 464 aa, and to Escherichia coli hypothetical symporter ydjn ydjn or b1729 SWALL:YDJN_ECOLI (SWALL:P77529) (463 aa) fasta scores: E(): 5e-135, 81.42% id in 463 aa; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (464 aa)    
Predicted Functional Partners:
cysJ
Sulfite reductase [NADPH] flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
   
  
 0.775
cysI
Sulfite reductase [NADPH] hemoprotein beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
   
  
 0.619
ECA2409
Conserved hypothetical protein; Similar to Escherichia coli, and Shigella flexneri hypothetical protein ydjm precursor ydjm or b1728 or sf1502 SWALL:YDJM_ECOLI (SWALL:P76209) (200 aa) fasta scores: E(): 1.1e-50, 62.3% id in 191 aa, and to Yersinia pestis putative membrane protein ypo1717 or y1879 SWALL:Q8ZFI6 (EMBL:AJ414150) (182 aa) fasta scores: E(): 1.2e-50, 67.58% id in 182 aa.
     
 0.594
ECA0070
Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
   
  
 0.580
cysD
Similar to Escherichia coli sulfate adenylyltransferase subunit 2 CysD or b2752 SWALL:CYSD_ECOLI (SWALL:P21156) (302 aa) fasta scores: E(): 5.1e-117, 92.05% id in 302 aa.
   
  
 0.570
cysH
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
   
  
 0.558
cysC
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
   
    0.554
cysP
Similar to Escherichia coli thiosulfate-binding protein precursor CysP or b2425 SWALL:CYSP_ECOLI (SWALL:P16700) (338 aa) fasta scores: E(): 1e-102, 79.34% id in 334 aa.
   
    0.551
cysN
Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
   
    0.551
cysM
Cysteine synthase B; Similar to Escherichia coli cysteine synthase B CysM SWALL:CYSM_ECOLI (SWALL:P16703) (303 aa) fasta scores: E(): 1e-83, 73.97% id in 292 aa; Belongs to the cysteine synthase/cystathionine beta- synthase family.
   
  
 0.434
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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