STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ECA2431Two-component response regulator; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri hypothetical response regulatory protein ypdb or b2381 or z3646 or ecs3261 or sf2444.2 SWALL:YPDB_ECOLI (SWALL:P77742) (244 aa) fasta scores: E(): 1.6e-73, 75.9% id in 249 aa, and to Klebsiella pneumoniae MrkE protein MrkE SWALL:MRKE_KLEPN (SWALL:P21649) (269 aa) fasta scores: E(): 1e-49, 73.4% id in 188 aa. (249 aa)    
Predicted Functional Partners:
ECA2432
Two-component sensor kinase; Similar to Escherichia coli, and Escherichia coli O157:H7 hypothetical protein ypda or b2380 or z3645 or ecs3260 SWALL:YPDA_ECOLI (SWALL:P76523) (565 aa) fasta scores: E(): 1.9e-161, 75.67% id in 559 aa, and to Fusobacterium nucleatum autolysin sensor kinase fn0220 SWALL:Q8R6B2 (EMBL:AE010534) (541 aa) fasta scores: E(): 1e-73, 40.89% id in 538 aa.
 
 0.998
ECA4152
Putative two-component system sensor kinase; Similar to Yersinia pestis putative membrane protein ypo3943 or y3885 SWALL:Q8ZA74 (EMBL:AJ414159) (565 aa) fasta scores: E(): 5.9e-173, 82.11% id in 559 aa, and to Shigella flexneri 2a str. 2457T putative 2-component sensor protein yehu or s2325 SWALL:AAP17542 (EMBL:AE016985) (561 aa) fasta scores: E(): 8e-149, 68.84% id in 552 aa.
 
 0.905
arcB
Similar to Escherichia coli, and Shigella flexneri aerobic respiration control sensor protein ArcB or b3210 or sf3250 SWALL:ARCB_ECOLI (SWALL:P22763) (778 aa) fasta scores: E(): 8.6e-180, 75.88% id in 788 aa, and to Yersinia pestis aerobic respiration control sensor/response regulatory protein ArcB SWALL:Q8ZB69 (EMBL:AJ414157) (778 aa) fasta scores: E(): 3.6e-190, 80.71% id in 788 aa.
    
 0.717
ECA2430
Putative membrane protein; Similar to Escherichia coli hypothetical protein yhjx or b3547 SWALL:YHJX_ECOLI (SWALL:P37662) (402 aa) fasta scores: E(): 1.7e-63, 45.99% id in 387 aa, and to Archaeoglobus fulgidus oxalate/formate antiporter af0367 SWALL:O29880 (EMBL:AE001079) (397 aa) fasta scores: E(): 6.5e-38, 32.33% id in 399 aa.
 
   
 0.706
rpfA
Two-component sensor kinase and response regulator; Similar to Pectobacterium carotovorum subsp. carotovorum sensor/regulator protein RpfA SWALL:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 92.88% id in 928 aa, and to Pectobacterium carotovorum subsp. carotovorum sensory kinase ExpS SWALL:O32556 (EMBL:Y13670) (928 aa) fasta scores: E(): 0, 95.36% id in 928 aa.
    
 0.568
ECA2433
Putative signaling protein; Similar to Caulobacter crescentus sensory box/ggdef family protein cc3094 SWALL:Q9A3V7 (EMBL:AE005972) (748 aa) fasta scores: E(): 3.4e-74, 34.06% id in 731 aa, and to Rhizobium loti hypothetical protein Mll7787 SWALL:Q984Y8 (EMBL:AP003012) (724 aa) fasta scores: E(): 1.7e-66, 37.17% id in 581 aa.
    
 0.530
rcsC
Two-component system sensor protein; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
 
  
 0.408
ECA2044
Putative membrane protein; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein yeaq or b1795 or c2200 or z2837 or ecs2504 SWALL:YEAQ_ECOLI (SWALL:P76246) (82 aa) fasta scores: E(): 5.4e-25, 85.18% id in 81 aa, and to Salmonella enterica subsp. enterica serovar Typhi Ty2 putative membrane protein SWALL:AAO68813 (EMBL:AE016838) (82 aa) fasta scores: E(): 9.8e-25, 83.95% id in 81 aa.
   
    0.407
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
  
    0.403
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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