STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hflDSimilar to Escherichia coli hypothetical protein ycfc or b1132 SWALL:YCFC_ECOLI (SWALL:P25746) (213 aa) fasta scores: E(): 2.3e-55, 71.98% id in 207 aa, and to Salmonella typhi hypothetical protein Sty1273 SWALL:Q8Z7H0 (EMBL:AL627269) (215 aa) fasta scores: E(): 7.5e-53, 68.59% id in 207 aa. (212 aa)    
Predicted Functional Partners:
trmU
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs; Belongs to the MnmA/TRMU family.
  
  
 0.960
ECA2367
Similar to Shigella flexneri orf, conserved hypothetical protein ycgl or sf1168 SWALL:AAN42784 (EMBL:AE015143) (108 aa) fasta scores: E(): 1.3e-25, 83.52% id in 85 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 protein ycgl or b1179 or c1627 or z1941 or ecs1674 SWALL:YCGL_ECOLI (SWALL:P76003) (108 aa) fasta scores: E(): 4e-25, 82.35% id in 85 aa.
  
  
 0.741
rnt
Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.
  
    0.727
purB
Adenylosuccinate lyase; Similar to Escherichia coli, and Escherichia coli O6 adenylosuccinate lyase PurB or b1131 or c1510 SWALL:PUR8_ECOLI (SWALL:P25739) (456 aa) fasta scores: E(): 1.8e-159, 88.81% id in 456 aa.
  
  
 0.672
dsbC
Thiol:disulfide interchange protein; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.
  
    0.655
nudJ
Putative MutT family protein; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri putative nudix hydrolase ymfb or b1134 or c1513 or z1863 or ecs1606 or sf1153 SWALL:YMFB_ECOLI (SWALL:P75965) (153 aa) fasta scores: E(): 2.6e-48, 75.67% id in 148 aa, and to Yersinia pestis hypothetical protein ypo1639 or y1800 SWALL:AAM85368 (EMBL:AJ414149) (148 aa) fasta scores: E(): 8.6e-46, 71.62% id in 148 aa.
 
    0.653
ECA1792
Similar to Yersinia pestis hypothetical protein ypo1594 or y1752 SWALL:Q8ZFU0 (EMBL:AJ414149) (174 aa) fasta scores: E(): 2.8e-56, 85.96% id in 171 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein yced or g30k or b1088 or c1358 or z1727 or ecs1466 SWALL:YCED_ECOLI (SWALL:P14189) (173 aa) fasta scores: E(): 1e-53, 79.76% id in 173 aa.
  
    0.631
truD
Conserved hypothetical protein; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.
  
    0.601
ECA2440
Similar to Yersinia pestis putative pseudouridine synthase ypo1640 or y1801 SWALL:Q8ZFQ3 (EMBL:AJ414149) (208 aa) fasta scores: E(): 9.5e-61, 69.71% id in 208 aa, and to Salmonella typhimurium putative ribosomal large subunit pseudouridine synthase ymfc or stm1237 SWALL:Q8ZPZ1 (EMBL:AE008754) (221 aa) fasta scores: E(): 4.4e-60, 69.44% id in 216 aa; Belongs to the pseudouridine synthase RsuA family.
       0.577
dsrE
Putative intracellular sulfur oxidation protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.
 
   
 0.563
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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