Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pehRTwo-component response regulator of virulence determinants; Similar to Pectobacterium carotovorum subsp. carotovorum response regulator PehR SWALL:Q9ZIN9 (EMBL:AF022772) (227 aa) fasta scores: E(): 1.5e-76, 91.26% id in 229 aa, and to Erwinia chrysanthemi PhoP protein phoP SWALL:CAD33237 (EMBL:AJ489252) (222 aa) fasta scores: E(): 7.2e-74, 87.83% id in 222 aa. (229 aa)    
Predicted Functional Partners:
pehS
Two-component sensor kinase, regulator of virulence determinants; Similar to Pectobacterium carotovorum subsp. carotovorum sensor protein PehS SWALL:Q9ZIN8 (EMBL:AF022772) (484 aa) fasta scores: E(): 6.6e-176, 92.35% id in 484 aa, and to Erwinia chrysanthemi PhoQ protein phoQ SWALL:CAD33238 (EMBL:AJ489252) (491 aa) fasta scores: E(): 4.1e-152, 76.97% id in 482 aa.
 
 0.999
arcB
Similar to Escherichia coli, and Shigella flexneri aerobic respiration control sensor protein ArcB or b3210 or sf3250 SWALL:ARCB_ECOLI (SWALL:P22763) (778 aa) fasta scores: E(): 8.6e-180, 75.88% id in 788 aa, and to Yersinia pestis aerobic respiration control sensor/response regulatory protein ArcB SWALL:Q8ZB69 (EMBL:AJ414157) (778 aa) fasta scores: E(): 3.6e-190, 80.71% id in 788 aa.
 
 0.977
rpfA
Two-component sensor kinase and response regulator; Similar to Pectobacterium carotovorum subsp. carotovorum sensor/regulator protein RpfA SWALL:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 92.88% id in 928 aa, and to Pectobacterium carotovorum subsp. carotovorum sensory kinase ExpS SWALL:O32556 (EMBL:Y13670) (928 aa) fasta scores: E(): 0, 95.36% id in 928 aa.
 
 0.955
pmrB
Two-component sensor kinase; Similar to Pectobacterium carotovorum subsp. carotovorum sensor kinase PmrB SWALL:CAE47080 (EMBL:AJ583007) (364 aa) fasta scores: E(): 1.5e-125, 94.78% id in 364 aa, and to Escherichia coli sensor protein BasS or PmrB or b4112 SWALL:BASS_ECOLI (SWALL:P30844) (363 aa) fasta scores: E(): 9.5e-69, 58.64% id in 353 aa.
 
 0.922
ECA3886
Putative membrane protein; Similar to the C-terminal region of many including Pseudomonas aeruginosa hypothetical protein Pa2870 SWALL:Q9HZX6 (EMBL:AE004713) (525 aa) fasta scores: E(): 1.9e-17, 39.39% id in 165 aa, and to Shewanella oneidensis ggdef domain protein so4457 SWALL:AAN57422 (EMBL:AE015878) (485 aa) fasta scores: E(): 2.1e-17, 39.03% id in 187 aa.
 
 0.904
cpxA
Two-component sensor kinase; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 sensor protein CpxA or EcfB or Ssd or Eup or b3911 or c4863 or z5456 or ecs4837 SWALL:CPXA_ECOLI (SWALL:P08336) (457 aa) fasta scores: E(): 1.8e-151, 80.04% id in 456 aa.
 
 0.903
envZ
Similar to Salmonella typhi osmolarity sensor protein envz envz or sty4295 or t4005 SWALL:ENVZ_SALTI (SWALL:P41406) (450 aa) fasta scores: E(): 2.2e-144, 84.1% id in 434 aa.
 
 0.875
phoR
Similar to Escherichia coli phosphate regulon sensor protein PhoR or NmpB or b0400 SWALL:PHOR_ECOLI (SWALL:P08400) (431 aa) fasta scores: E(): 1e-129, 74.65% id in 430 aa, and to Yersinia pestis phosphate regulon sensor protein PhoR or ypo3204 or y0979 SWALL:AAM84560 (EMBL:AJ414155) (438 aa) fasta scores: E(): 9.4e-148, 83.06% id in 437 aa.
 
 0.858
baeS
Two-component system sensor kinase; Similar to Escherichia coli sensor protein BaeS or b2078 SWALL:BAES_ECOLI (SWALL:P30847) (467 aa) fasta scores: E(): 3.1e-113, 65.06% id in 458 aa.
 
 0.824
rcsD
Putative two-component system sensor kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
 
 0.808
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.