STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ptrBProtease II; Similar to Escherichia coli protease II PtrB or Tlp or b1845 SWALL:PTRB_ECOLI (SWALL:P24555) (686 aa) fasta scores: E(): 2e-180, 63.93% id in 671 aa. (683 aa)    
Predicted Functional Partners:
ptrA
Similar to Escherichia coli protease III precursor PtrA or Ptr or b2821 SWALL:PTRA_ECOLI (SWALL:P05458) (962 aa) fasta scores: E(): 0, 63.68% id in 950 aa, and to Yersinia pestis protease III ptra or ypo1019 or ptr or y3165 SWALL:Q8ZH89 (EMBL:AJ414146) (962 aa) fasta scores: E(): 0, 68.02% id in 960 aa; Belongs to the peptidase M16 family.
      
 0.707
srfC
Putative virulence factor; Similar to Salmonella typhimurium SrfC or stm1595 SWALL:Q9KIJ8 (EMBL:AF231758) (714 aa) fasta scores: E(): 4.2e-23, 30.06% id in 795 aa, and to Yersinia pestis putative virulence factor y2123 SWALL:AAM85685 (EMBL:AE013815) (846 aa) fasta scores: E(): 2.9e-65, 55.12% id in 849 aa.
      
 0.503
clpP
ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
  
 0.497
glnE
Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]
      
 0.497
purT
Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.
       0.493
scrR
Sucrose operon repressor; Similar to Erwinia amylovora repressor scrR SWALL:Q9F497 (EMBL:AJ250722) (342 aa) fasta scores: E(): 4.7e-86, 65.46% id in 333 aa, and to Klebsiella pneumoniae sucrose operon repressor scrR SWALL:SCRR_KLEPN (SWALL:P37076) (334 aa) fasta scores: E(): 5.5e-88, 65.07% id in 335 aa.
      
 0.471
scrB
Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.
      
 0.463
rlpA
Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
  
  
 0.441
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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