STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptrBProtease II; Similar to Escherichia coli protease II PtrB or Tlp or b1845 SWALL:PTRB_ECOLI (SWALL:P24555) (686 aa) fasta scores: E(): 2e-180, 63.93% id in 671 aa. (683 aa)    
Predicted Functional Partners:
ptrA
Similar to Escherichia coli protease III precursor PtrA or Ptr or b2821 SWALL:PTRA_ECOLI (SWALL:P05458) (962 aa) fasta scores: E(): 0, 63.68% id in 950 aa, and to Yersinia pestis protease III ptra or ypo1019 or ptr or y3165 SWALL:Q8ZH89 (EMBL:AJ414146) (962 aa) fasta scores: E(): 0, 68.02% id in 960 aa; Belongs to the peptidase M16 family.
      
 0.631
srfC
Putative virulence factor; Similar to Salmonella typhimurium SrfC or stm1595 SWALL:Q9KIJ8 (EMBL:AF231758) (714 aa) fasta scores: E(): 4.2e-23, 30.06% id in 795 aa, and to Yersinia pestis putative virulence factor y2123 SWALL:AAM85685 (EMBL:AE013815) (846 aa) fasta scores: E(): 2.9e-65, 55.12% id in 849 aa.
      
 0.555
purT
Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.
       0.493
scrR
Sucrose operon repressor; Similar to Erwinia amylovora repressor scrR SWALL:Q9F497 (EMBL:AJ250722) (342 aa) fasta scores: E(): 4.7e-86, 65.46% id in 333 aa, and to Klebsiella pneumoniae sucrose operon repressor scrR SWALL:SCRR_KLEPN (SWALL:P37076) (334 aa) fasta scores: E(): 5.5e-88, 65.07% id in 335 aa.
      
 0.478
scrB
Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.
      
 0.459
rlpA
Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
  
   
 0.455
ECA0980
Autotransporter; Similar to Pseudomonas fluorescens serine protease homologue PspB SWALL:Q9ZNI5 (EMBL:AB015053) (1036 aa) fasta scores: E(): 1.6e-25, 28.66% id in 1106 aa, and to Serratia marcescens extracellular serine protease precursor SWALL:PRTT_SERMA (SWALL:P29805) (1045 aa) fasta scores: E(): 1.1e-16, 25.6% id in 1082 aa.
 
   
 0.454
clpP
ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
  
 0.433
ECA1177
Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
  
  
 0.430
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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