Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (491 aa)    
Predicted Functional Partners:
gnd
6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
 0.993
pgi
Glucose-6-phosphate isomerase; Similar to Escherichia coli, and Escherichia coli O157:H7 glucose-6-phosphate isomerase Pgi or b4025 or z5623 or ecs5008 SWALL:G6PI_ECOLI (SWALL:P11537) (549 aa) fasta scores: E(): 1.4e-193, 86.86% id in 548 aa.
  
 
 0.987
glk
Glucokinase; Similar to Escherichia coli, and Escherichia coli O157:H7 glucokinase Glk or b2388 or z3654 or ecs3268 SWALL:GLK_ECOLI (SWALL:P46880) (321 aa) fasta scores: E(): 7.3e-98, 76.32% id in 321 aa; Belongs to the bacterial glucokinase family.
 
 
 0.985
pgl
Conserved hypothetical protein; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate.
    
 0.974
pgm
Phosphoglucomutase; Similar to Escherichia coli phosphoglucomutase Pgm or b0688 SWALL:PGMU_ECOLI (SWALL:P36938) (546 aa) fasta scores: E(): 5e-188, 87.72% id in 546 aa.
  
 0.972
gapA
Glyceraldehyde 3-phosphate dehydrogenase a; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri glyceraldehyde 3-phosphate dehydrogenase A GapA or b1779 or c2184 or z2818 or ecs2488 or sf1444 SWALL:G3P1_ECOLI (SWALL:P06977) (330 aa) fasta scores: E(): 3.2e-112, 90.6% id in 330 aa; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 0.972
pykA
Pyruvate kinase II; Similar to Escherichia coli pyruvate kinase ii PykA or b1854 SWALL:KPY2_ECOLI (SWALL:P21599) (479 aa) fasta scores: E(): 2.7e-156, 91.23% id in 479 aa.
  
 
 0.971
tpiA-2
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
   
 
 0.967
pykF
Pyruvate kinase; Similar to Escherichia coli, and Escherichia coli O157:H7 pyruvate kinase I PykF or b1676 or z2704 or ecs2383 SWALL:KPY1_ECOLI (SWALL:P14178) (470 aa) fasta scores: E(): 4.4e-139, 84.68% id in 470 aa.
  
 
 0.965
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
   
 
 0.965
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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