STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hexRSimilar to Escherichia coli hex regulon repressor HexR or b1853 SWALL:HEXR_ECOLI (SWALL:P46118) (289 aa) fasta scores: E(): 3.1e-87, 82.51% id in 286 aa, and to Yersinia pestis hex regulon repressor HexR or ypo2065 SWALL:Q8ZET8 (EMBL:AJ414151) (289 aa) fasta scores: E(): 1.1e-91, 87.41% id in 286 aa. (289 aa)    
Predicted Functional Partners:
eda
Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri Khg/kdpg aldolase [includes: 4-hydroxy-2-oxoglutarate aldolase and 2- dehydro-3-deoxyphosphogluconate aldolase Eda or Hga or KdgA or b1850 or c2263 or z2902 or ecs2560 or sf1860 SWALL:ALKH_ECOLI (SWALL:P10177) (213 aa) fasta scores: E(): 1.2e-67, 89.15% id in 212 aa, and to Erwinia chrysanthemi khg/kdpg aldolase [includes: 4-hydroxy-2-oxoglutarate aldolase Eda or KdgA SWALL:ALKH_ERWCH (SWALL:P38448) (213 aa) fasta scores: E(): 7e-67, 89.2% id in 213 aa.
 
   
 0.811
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 
   
 0.764
edd
Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.
 
   
 0.753
nagE
Similar to Escherichia coli PTS system, N-acetylglucosamine-specific IIABC component NagE or pPstN or b0679 SWALL:PTAA_ECOLI (SWALL:P09323) (648 aa) fasta scores: E(): 7.8e-62, 45.16% id in 496 aa.
 
  
 0.519
hfq
Putative phage-related protein (host factor-I protein); RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
      
 0.509
fis
DNA-binding protein; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.
      
 0.492
kdgF
Similar to Erwinia chrysanthemi pectin degradation protein KdgF SWALL:KDGF_ERWCH (SWALL:Q05527) (110 aa) fasta scores: E(): 3.3e-38, 89.09% id in 110 aa, and to Yersinia pestis putative pectin degradation protein KdgF or y1888 SWALL:AAM85455 (EMBL:AE013792) (116 aa) fasta scores: E(): 2.9e-33, 77.98% id in 109 aa.
      
 0.475
ECA3228
Similar to Oceanobacillus iheyensis transcriptional regulator ob0613 SWALL:BAC12569 (EMBL:AP004595) (282 aa) fasta scores: E(): 6e-11, 28.13% id in 263 aa, and to Haemophilus influenzae hypothetical protein Hi0143 hi0143 SWALL:Y143_HAEIN (SWALL:P44540) (288 aa) fasta scores: E(): 2.8e-09, 26.1% id in 226 aa.
  
     0.472
kdgT
2-keto-3-deoxygluconate permease; The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system. Belongs to the KdgT transporter family.
      
 0.472
sun
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
      
 0.451
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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