STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA2483Putative peptidase; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri hypothetical metalloprotease yeba precursor yeba or b1856 or c2270 or sf1866 SWALL:YEBA_ECOLI (SWALL:P24204) (440 aa) fasta scores: E(): 6.7e-128, 75.11% id in 442 aa, and to Salmonella typhimurium putative peptidase yeba or stm1890 SWALL:Q8ZNV9 (EMBL:AE008784) (439 aa) fasta scores: E(): 5.8e-128, 75.05% id in 441 aa. (440 aa)    
Predicted Functional Partners:
znuA
Similar to Escherichia coli high-affinity zinc uptake system protein ZnuA precursor ZnuA or b1857 SWALL:ZNUA_ECOLI (SWALL:P39172) (310 aa) fasta scores: E(): 4.6e-47, 61.05% id in 321 aa.
 
  
 0.923
ompN
Similar to Escherichia coli outer membrane protein N precursor OmpN or b1377 SWALL:OMPN_ECOLI (SWALL:P77747) (377 aa) fasta scores: E(): 1.1e-76, 53.86% id in 388 aa.
  
   
 0.795
ftsN
Cell division protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.
 
  
 0.701
amiB
Similar to Escherichia coli N-acetylmuramoyl-L-alanine amidase AmiB precursor AmiB or b4169 SWALL:AMIB_ECOLI (SWALL:P26365) (445 aa) fasta scores: E(): 5.9e-74, 65.34% id in 430 aa.
 
  
 0.693
msbB
Lipid A biosynthesis (KDO)2-(lauroyl)-lipid iva acyltransferase; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A.
 
  
 0.689
ECA0304
Similar to Yersinia pestis putative membrane protein ypo3565 SWALL:AAM83730 (EMBL:AJ414157) (134 aa) fasta scores: E(): 1.5e-41, 87.97% id in 133 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein YhcB SWALL:YHCB_ECOLI (SWALL:P39436) (134 aa) fasta scores: E(): 5.6e-34, 80.31% id in 127 aa.
  
     0.680
holD
DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.
  
     0.673
ecfE
Protease; Similar to Escherichia coli, and Escherichia coli O157:H7 protease EcfE or b0176 or z0187 or ecs0178 SWALL:ECFE_ECOLI (SWALL:P37764) (450 aa) fasta scores: E(): 3.8e-131, 73.83% id in 451 aa, and to Salmonella typhimurium protease EcfE or stm0223 SWALL:ECFE_SALTY (SWALL:Q8ZRP1) (450 aa) fasta scores: E(): 1.9e-138, 78.27% id in 451 aa.
 
  
 0.672
mltD
Similar to Escherichia coli, and Escherichia coli O6 membrane-bound lytic murein transglycosylase D precursor MltD or DniR or b0211 or c0248 SWALL:MLTD_ECOLI (SWALL:P23931) (452 aa) fasta scores: E(): 7e-113, 66.81% id in 464 aa.
 
  
 0.659
rcsD
Putative two-component system sensor kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
  
  
 0.652
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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