| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| copA | cutC | ECA1193 | ECA2518 | Similar to Escherichia coli copper-transporting P-type ATPase CopA or b0484 SWALL:ATCU_ECOLI (SWALL:Q59385) (833 aa) fasta scores: E(): 4.8e-208, 71.37% id in 835 aa. | Copper homeostasis protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | 0.613 |
| cutC | copA | ECA2518 | ECA1193 | Copper homeostasis protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | Similar to Escherichia coli copper-transporting P-type ATPase CopA or b0484 SWALL:ATCU_ECOLI (SWALL:Q59385) (833 aa) fasta scores: E(): 4.8e-208, 71.37% id in 835 aa. | 0.613 |
| cutC | gidA | ECA2518 | ECA4521 | Copper homeostasis protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.493 |
| cutC | glmU | ECA2518 | ECA4509 | Copper homeostasis protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | Bifunctional GlmU protein [includes: UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferas [...] | 0.467 |
| cutC | lepA | ECA2518 | ECA3280 | Copper homeostasis protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | GTP-binding protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.522 |
| cutC | metK | ECA2518 | ECA3920 | Copper homeostasis protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.559 |
| cutC | nadE | ECA2518 | ECA2412 | Copper homeostasis protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | NH3-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.652 |
| cutC | nagA | ECA2518 | ECA1325 | Copper homeostasis protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | N-acetylglucosamine-6-phosphate deacetylase; Similar to Escherichia coli, and Escherichia coli O157:H7 N-acetylglucosamine-6-phosphate deacetylase NagA or b0677 or z0824 or ecs0707 SWALL:NAGA_ECOLI (SWALL:P15300) (382 aa) fasta scores: E(): 1.7e-109, 72.55% id in 379 aa. | 0.472 |
| cutC | nagB | ECA2518 | ECA1326 | Copper homeostasis protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.643 |
| cutC | nagE | ECA2518 | ECA1327 | Copper homeostasis protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | Similar to Escherichia coli PTS system, N-acetylglucosamine-specific IIABC component NagE or pPstN or b0679 SWALL:PTAA_ECOLI (SWALL:P09323) (648 aa) fasta scores: E(): 7.8e-62, 45.16% id in 496 aa. | 0.509 |
| cutC | secD | ECA2518 | ECA1122 | Copper homeostasis protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | Protein-export membrane protei; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.465 |
| gidA | cutC | ECA4521 | ECA2518 | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | Copper homeostasis protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | 0.493 |
| gidA | glmU | ECA4521 | ECA4509 | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | Bifunctional GlmU protein [includes: UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferas [...] | 0.535 |
| gidA | lepA | ECA4521 | ECA3280 | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | GTP-binding protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.551 |
| gidA | secD | ECA4521 | ECA1122 | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | Protein-export membrane protei; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.453 |
| glmU | cutC | ECA4509 | ECA2518 | Bifunctional GlmU protein [includes: UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferas [...] | Copper homeostasis protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | 0.467 |
| glmU | gidA | ECA4509 | ECA4521 | Bifunctional GlmU protein [includes: UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferas [...] | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.535 |
| glmU | lepA | ECA4509 | ECA3280 | Bifunctional GlmU protein [includes: UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferas [...] | GTP-binding protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.531 |
| glmU | secD | ECA4509 | ECA1122 | Bifunctional GlmU protein [includes: UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferas [...] | Protein-export membrane protei; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.454 |
| lepA | cutC | ECA3280 | ECA2518 | GTP-binding protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Copper homeostasis protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | 0.522 |
