Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mviMSimilar to Salmonella typhimurium virulence factor MviM or stm1169 SWALL:MVIM_SALTY (SWALL:P37168) (307 aa) fasta scores: E(): 2.9e-71, 63.3% id in 297 aa, and to Escherichia coli virulence factor MviM homolog MviM or b1068 SWALL:MVIM_ECOLI (SWALL:P75931) (307 aa) fasta scores: E(): 1.2e-67, 60% id in 300 aa. (321 aa)    
Predicted Functional Partners:
ECA2523
Similar to Escherichia coli hypothetical protein yceh or b1067 SWALL:YCEH_ECOLI (SWALL:P29217) (215 aa) fasta scores: E(): 2e-56, 72.64% id in 212 aa, and to Salmonella typhimurium, and Salmonella typhi putative cytoplasmic protein yceh or stm1168 or sty1206 SWALL:Q8XF09 (EMBL:AE008750) (215 aa) fasta scores: E(): 1.9e-54, 69.81% id in 212 aa; Belongs to the UPF0502 family.
  
    0.854
rimJ
Ribosomal-protein-alanine acetyltransferase; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri ribosomal-protein-alanine acetyltransferase RimJ or b1066 or z1703 or ecs1444 or sf1072 SWALL:RIMJ_ECOLI (SWALL:P09454) (194 aa) fasta scores: E(): 3.3e-67, 77.31% id in 194 aa.
  
    0.719
mviN
Putative virulence factor; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
     
 0.643
ECA2847
Similar to Yersinia pestis hypothetical protein ypo2434 or y1902 SWALL:Q8ZDW4 (EMBL:AJ414152) (70 aa) fasta scores: E(): 4.7e-15, 67.14% id in 70 aa, and to Caulobacter crescentus hypothetical protein Cc0128 SWALL:Q9ABU2 (EMBL:AE005687) (66 aa) fasta scores: E(): 2.2e-05, 43.54% id in 62 aa.
 
    0.569
lysS
Lysyl tRNA synthetase; Similar to Escherichia coli, and Escherichia coli O6 lysyl-tRNA synthetase LysS SWALL:SYK1_ECOLI (SWALL:P13030) (504 aa) fasta scores: E(): 1.9e-174, 85.71% id in 504 aa; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
    0.538
nusB
N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
     
 0.537
msbA
Lipid a export ATP-binding/permease; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
     
 0.537
ftsA
Cell division protein; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
      
 0.530
wecH
Putative membrane protein; Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units.
  
     0.528
groL
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
      
 0.499
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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