Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ECA2529Putative phosphoesterase; Similar to Yersinia pestis hypothetical protein Ypo2037 SWALL:Q8ZEW6 (EMBL:AJ414151) (245 aa) fasta scores: E(): 1.1e-84, 84.89% id in 245 aa, and to Salmonella typhimurium, and Salmonella typhi putative histidinol phosphatase and related hydrolases of the php family ycdx or stm1136 or sty1173 SWALL:Q8XGW8 (EMBL:AE008749) (245 aa) fasta scores: E(): 1.8e-76, 75.1% id in 245 aa. (245 aa)    
Predicted Functional Partners:
hisB
Similar to Escherichia coli histidine biosynthesis bifunctional protein HisB [includes: histidinol-phosphatase and imidazoleglycerol-phosphate dehydratase] HisB or b2022 SWALL:HIS7_ECOLI (SWALL:P06987) (355 aa) fasta scores: E(): 1.6e-119, 82.81% id in 355 aa.
  
 
 0.890
hisI
Similar to Escherichia coli histidine biosynthesis bifunctional protein HisIE [includes: phosphoribosyl-AMP cyclohydrolase and phosphoribosyl-ATP pyrophosphatase HisI or hisie or b2026 SWALL:HIS2_ECOLI (SWALL:P06989) (203 aa) fasta scores: E(): 2e-64, 80.09% id in 201 aa; In the N-terminal section; belongs to the PRA-CH family.
  
 
 0.876
ECA2528
Similar to Yersinia pestis hypothetical protein ypo2038 or y2274 SWALL:AAM85834 (EMBL:AJ414151) (186 aa) fasta scores: E(): 2.8e-45, 67.22% id in 180 aa, and to Escherichia coli hypothetical protein ycdy or b1035 SWALL:YCDY_ECOLI (SWALL:P75915) (184 aa) fasta scores: E(): 1.1e-41, 60.42% id in 187 aa.
  
 
 0.873
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
 
 0.552
ybeY
Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
   
    0.528
ECA3947
Similar to Pseudomonas putida D-isomer specific 2-hydroxyacid dehydrogenase family protein pp4589 SWALL:AAN70162 (EMBL:AE016791) (310 aa) fasta scores: E(): 4.3e-61, 56.63% id in 309 aa, and to Pseudomonas aeruginosa probable 2-hydroxyacid dehydrogenase pa1296 SWALL:Q9I448 (EMBL:AE004559) (310 aa) fasta scores: E(): 5.3e-54, 51.94% id in 308 aa.
  
  
 0.514
ECA2432
Two-component sensor kinase; Similar to Escherichia coli, and Escherichia coli O157:H7 hypothetical protein ypda or b2380 or z3645 or ecs3260 SWALL:YPDA_ECOLI (SWALL:P76523) (565 aa) fasta scores: E(): 1.9e-161, 75.67% id in 559 aa, and to Fusobacterium nucleatum autolysin sensor kinase fn0220 SWALL:Q8R6B2 (EMBL:AE010534) (541 aa) fasta scores: E(): 1e-73, 40.89% id in 538 aa.
  
     0.494
ECA3043
Putative phosphoesterase; Similar to Salmonella typhimurium, and Salmonella typhi putative phosphoesterase yfce or stm2347 or sty2577 SWALL:Q8XGM7 (EMBL:AE008805) (183 aa) fasta scores: E(): 5.3e-49, 71.27% id in 181 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein yfce or b2300 or c2843 or z3562 or ecs3184 SWALL:YFCE_ECOLI (SWALL:P76495) (184 aa) fasta scores: E(): 1.1e-50, 72.37% id in 181 aa.
 
  
 0.491
gltB
Similar to Escherichia coli glutamate synthase [NADPH] large chain precursor GltB or AspB SWALL:GLTB_ECOLI (SWALL:P09831) (1517 aa) fasta scores: E(): 0, 86.75% id in 1495 aa, and to Yersinia pestis glutamate synthase, large subunit GltB SWALL:AAM83722 (EMBL:AE013613) (1535 aa) fasta scores: E(): 0, 90.25% id in 1498 aa.
  
  
 0.454
ECA1344
Similar to Yersinia pestis putative membrane protein ypo2693 SWALL:Q8ZD95 (EMBL:AJ414153) (68 aa) fasta scores: E(): 4.2e-22, 73.52% id in 68 aa, and to Salmonella typhimurium putative periplasmic protein ybfa or stm0708 SWALL:Q8ZQV9 (EMBL:AE008728) (68 aa) fasta scores: E(): 3.2e-20, 72.05% id in 68 aa.
  
     0.452
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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