STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA2536Similar to Yersinia pestis putative iron-sulfur binding protein ypo1417 or y2752 SWALL:Q8ZG89 (EMBL:AJ414148) (370 aa) fasta scores: E(): 1.8e-107, 70.76% id in 366 aa, and to Salmonella typhimurium putative iron-sulfur protein stm1060 SWALL:Q8ZQ74 (EMBL:AE008746) (369 aa) fasta scores: E(): 1.3e-97, 65.04% id in 369 aa. (367 aa)    
Predicted Functional Partners:
nuoC
NADH-quinone oxidoreductase chain C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
  
 
 0.946
hcr
Similar to Escherichia coli NADH oxidoreductase Hcr or b0872 SWALL:HCR_ECOLI (SWALL:P75824) (322 aa) fasta scores: E(): 1.3e-46, 61.14% id in 332 aa.
  
 0.907
cysJ
Sulfite reductase [NADPH] flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
   
 0.880
cfa6
Similar to Pseudomonas syringae type I polyketide synthase Cfa6 SWALL:Q9Z3T9 (EMBL:AF098795) (2731 aa) fasta scores: E(): 0, 60.14% id in 2725 aa, and to Polyangium cellulosum Soraphen polyketide synthase A SorA SWALL:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 0, 43.21% id in 2277 aa.
 
 0.847
nfuA
Conserved hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
 0.770
fumA
Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
 0.681
cysI
Sulfite reductase [NADPH] hemoprotein beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
 0.657
ECA3662
Putative cytochrome; Similar to Bacillus halodurans cytochrome P450 hydroxylase bh0579 SWALL:Q9KFA6 (EMBL:AP001509) (453 aa) fasta scores: E(): 2.2e-24, 26.19% id in 462 aa, and to Vicia sativa cytochrome P450 94a1 cyp94a1 or vagh111 SWALL:C941_VICSA (SWALL:O81117) (514 aa) fasta scores: E(): 2.2e-23, 25.88% id in 483 aa.
 
 0.657
nasB
Similar to Klebsiella pneumoniae nitrite reductase [NAD(P)H] large subunit NasB SWALL:NIRB_KLEPN (SWALL:Q06458) (957 aa) fasta scores: E(): 0, 70.89% id in 962 aa; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
 
 0.646
aegA
Anaerobically expressed oxidoreductase; Similar to Escherichia coli aega protein AegA or b2468 SWALL:AEGA_ECOLI (SWALL:P37127) (659 aa) fasta scores: E(): 3.7e-149, 61.43% id in 656 aa, and to Salmonella typhimurium putative oxidoreductase aega or stm2479 SWALL:Q8ZN79 (EMBL:AE008811) (653 aa) fasta scores: E(): 6e-147, 60.7% id in 649 aa.
   
 0.619
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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