STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
asnSasparaginyl-tRNA synthetase; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri asparaginyl-tRNA synthetase AsnS or Tss or b0930 or c1072 or sf0927 SWALL:SYN_ECOLI (SWALL:P17242) (465 aa) fasta scores: E(): 4.4e-172, 86.88% id in 465 aa. (466 aa)    
Predicted Functional Partners:
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
 0.959
argS
Similar to Escherichia coli arginyl-tRNA synthetase ArgS or b1876 SWALL:SYR_ECOLI (SWALL:P11875) (577 aa) fasta scores: E(): 4.1e-183, 80.24% id in 577 aa.
  
 0.937
proS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]
  
 0.937
leuS
Similar to Escherichia coli leucyl-tRNA synthetase LeuS or b0642 SWALL:SYL_ECOLI (SWALL:P07813) (860 aa) fasta scores: E(): 0, 84.3% id in 860 aa; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.935
ileS
isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
   
 0.912
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
  
 
 0.832
gltX
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
 
 0.812
glnS
Similar to Escherichia coli glutaminyl-tRNA synthetase GlnS or b0680 SWALL:SYQ_ECOLI (SWALL:P00962) (553 aa) fasta scores: E(): 8.8e-203, 85.42% id in 549 aa.
 
 0.811
ECA2141
Probable amidase; Similar to Pseudomonas putida amidase SWALL:AMID_PSEPU (SWALL:O69768) (466 aa) fasta scores: E(): 2.4e-24, 31.03% id in 435 aa, and to the N-terminal region of Saccharomyces cerevisiae urea amidolyase [includes: urea carboxylase and allophanate hydrolase] Dur1,2 or ybr208c or ybr1448 SWALL:DUR1_YEAST (SWALL:P32528) (1835 aa) fasta scores: E(): 2.9e-65, 43.25% id in 608 aa.
   
 0.738
ECA3499
Probable amidase; Similar to Yersinia pestis probable amidase ypo3261 or y0928 SWALL:Q8ZBX3 (EMBL:AJ414156) (465 aa) fasta scores: E(): 5.1e-122, 70.11% id in 455 aa, and to Pseudomonas sp. biuret hydrolase atzE SWALL:Q936X3 (EMBL:U66917) (457 aa) fasta scores: E(): 2e-87, 53.09% id in 452 aa.
   
 0.738
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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