Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ompNSimilar to Escherichia coli outer membrane protein N precursor OmpN or b1377 SWALL:OMPN_ECOLI (SWALL:P77747) (377 aa) fasta scores: E(): 1.1e-76, 53.86% id in 388 aa. (370 aa)    
Predicted Functional Partners:
vacJ
Lipoprotein; Similar to Shigella flexneri VacJ lipoprotein precursor VacJ or sf2424 SWALL:VACJ_SHIFL (SWALL:P43262) (251 aa) fasta scores: E(): 1.2e-75, 71.71% id in 251 aa, and to Yersinia pestis vacj lipoprotein VacJ or ypo2743 SWALL:Q8ZD49 (EMBL:AJ414153) (254 aa) fasta scores: E(): 3.3e-80, 76.68% id in 253 aa.
   
 
 0.860
tolC
Similar to Escherichia coli outer membrane protein TolC precursor TolC or MtcB or MukA or RefI or b3035 SWALL:TOLC_ECOLI (SWALL:P02930) (495 aa) fasta scores: E(): 4.1e-124, 75.32% id in 466 aa, and to Erwinia chrysanthemi outer membrane protein TolC SWALL:Q93AG1 (EMBL:AF421372) (472 aa) fasta scores: E(): 2.3e-128, 77.89% id in 466 aa.
  
  
 0.836
ECA0943
Similar to Escherichia coli f15 P-fimbriae major subunit precursor FfiA SWALL:P71218 (EMBL:Y08929) (168 aa) fasta scores: E(): 2.8e-17, 38.5% id in 174 aa, and to Serratia marcescens fimbria A protein precursor SmfA SWALL:FMA_SERMA (SWALL:P13421) (174 aa) fasta scores: E(): 1.3e-16, 39.34% id in 183 aa.
  
  
 0.787
ompA
Outer-membrane protein A; Similar to Erwinia carotovora putative outer-membrane protein a precursor OmpA SWALL:Q9RM69 (EMBL:AJ249340) (367 aa) fasta scores: E(): 2.6e-120, 90.32% id in 372 aa, and to Serratia marcescens outer membrane protein a precursor OmpA SWALL:OMPA_SERMA (SWALL:P04845) (359 aa) fasta scores: E(): 4.8e-71, 75.61% id in 369 aa; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
  
 
 0.781
tolB
TolB protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
 
 
 
 0.780
rcsD
Putative two-component system sensor kinase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
  
  
 0.774
zapB
Conserved hypothetical protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.
  
     0.773
holD
DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.
  
     0.772
uspA
Universal stress protein A; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri universal stress protein A UspA or b3495 or c4293 or z4895 or ecs4367 or sf3526 SWALL:USPA_ECOLI (SWALL:P28242) (143 aa) fasta scores: E(): 6.7e-47, 94.36% id in 142 aa.
  
  
 0.771
ECA0304
Similar to Yersinia pestis putative membrane protein ypo3565 SWALL:AAM83730 (EMBL:AJ414157) (134 aa) fasta scores: E(): 1.5e-41, 87.97% id in 133 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein YhcB SWALL:YHCB_ECOLI (SWALL:P39436) (134 aa) fasta scores: E(): 5.6e-34, 80.31% id in 127 aa.
  
   
 0.771
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.