STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA2545Similar to Yersinia pestis putative exported protein ypo1408 or y2762 SWALL:Q8ZG97 (EMBL:AJ414148) (182 aa) fasta scores: E(): 4.6e-60, 82.41% id in 182 aa, and to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri hypothetical protein ycbk or b0926 or c1068 or z1273 or ecs1009 or sf0923 SWALL:YCBK_ECOLI (SWALL:P75848) (182 aa) fasta scores: E(): 5.1e-56, 78.57% id in 182 aa. (182 aa)    
Predicted Functional Partners:
ECA2546
Similar to Yersinia pestis putative exported protein ypo1407 or y2763 SWALL:AAM86315 (EMBL:AJ414148) (618 aa) fasta scores: E(): 1.4e-92, 60.48% id in 615 aa, and to Vibrio cholerae hypothetical protein Vc1268 SWALL:Q9KSI8 (EMBL:AE004206) (524 aa) fasta scores: E(): 7.1e-47, 36.56% id in 495 aa.
 
   
 0.885
ECA2544
Conserved hypothetical protein; Similar to Yersinia pestis metallo-beta-lactamase superfamily protein ypo1409 or y2761 SWALL:Q8ZG96 (EMBL:AJ414148) (215 aa) fasta scores: E(): 8.9e-67, 72.55% id in 215 aa, and to Escherichia coli hypothetical protein ycbl or b0927 SWALL:YCBL_ECOLI (SWALL:P75849) (215 aa) fasta scores: E(): 3.5e-65, 70.23% id in 215 aa; putative metallo-beta-lactamase.
  
    0.851
mepA
Penicillin-insensitive murein endopeptidase; Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus. Belongs to the peptidase M74 family.
  
     0.739
ECA0111
Conserved hypothetical protein; Similar to Escherichia coli O6 putative GumP homolog c1691 SWALL:AAN80158 (EMBL:AE016760) (268 aa) fasta scores: E(): 3.6e-70, 63.43% id in 268 aa, and to Yersinia pestis hypothetical y2332 SWALL:AAM85891 (EMBL:AE013835) (283 aa) fasta scores: E(): 2.2e-69, 62.68% id in 268 aa, and to Xanthomonas axonopodis GumP protein SWALL:Q8PJG2 (EMBL:AE011897) (282 aa) fasta scores: E(): 8.9e-25, 35.71% id in 266 aa.
  
    0.551
ECA2849
Metallo-beta-lactamase; Similar to Xanthomonas maltophilia metallo-beta-lactamase precursor BlaS SWALL:Q9F238 (EMBL:AJ291672) (290 aa) fasta scores: E(): 9.3e-15, 29.24% id in 277 aa, and to Fluoribacter gormanii metallo-beta-lactamase Fez-1 protein blafez-1 SWALL:Q9K578 (EMBL:Y17896) (282 aa) fasta scores: E(): 7e-16, 29.04% id in 241 aa, and to Xanthomonas maltophilia metallo-beta-lactamase l1 precursor SWALL:BLA1_XANMA (SWALL:P52700) (290 aa) fasta scores: E(): 5.2e-14, 30.21% id in 235 aa.
  
    0.551
ECA2979
Probable hydrolase; Similar to Pseudomonas sp. WBC-3 methyl parathion hydrolase mpD SWALL:Q841S6 (EMBL:AY251554) (331 aa) fasta scores: E(): 2.6e-22, 31.57% id in 285 aa, and to Plesiomonas sp. DLL-1 methyl parathion degrading protein SWALL:Q93SP1 (EMBL:AY029773) (341 aa) fasta scores: E(): 2.6e-22, 31.57% id in 285 aa.
  
    0.495
ECA3777
Similar to Salmonella typhi hypothetical upf0231 protein yacl or sty0182 or t0165 SWALL:Q8Z9E5 (EMBL:AL627265) (120 aa) fasta scores: E(): 1.2e-33, 70.94% id in 117 aa, and to Escherichia coli O6 hypothetical upf0231 protein yacl or c0148 SWALL:AAN78642 (EMBL:AE016755) (136 aa) fasta scores: E(): 3.5e-32, 70.08% id in 117 aa.
  
     0.450
gloB
Probable hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
  
    0.429
meh
Metallo hydrolase; Similar to Erwinia chrysanthemi metallo hydrolase precursor Meh SWALL:CAC83617 (EMBL:AJ292045) (324 aa) fasta scores: E(): 8.6e-80, 65.64% id in 326 aa, and to Plesiomonas sp. M6 methyl parathion hydrolase Mpd SWALL:Q9ALW1 (EMBL:AF338729) (331 aa) fasta scores: E(): 1.8e-46, 47.5% id in 320 aa. Also similar to ECA3557 (52.761% id. in 326 aa overlap).
   
    0.428
ECA3557
Metallo hydrolase; Similar to Erwinia chrysanthemi metallo hydrolase precursor Meh SWALL:CAC83617 (EMBL:AJ292045) (324 aa) fasta scores: E(): 1.8e-68, 56% id in 325 aa, and to Plesiomonas sp. DLL-1 methyl parathion degrading protein SWALL:Q93SP1 (EMBL:AY029773) (341 aa) fasta scores: E(): 5e-49, 47.41% id in 310 aa. Also similar to ECA3555 (52.761% id. in 326 aa overlap).
   
    0.428
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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