| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| carB | dusB | ECA3870 | ECA0256 | Similar to Escherichia coli carbamoyl-phosphate synthase large chain CarB or PyrA or b0033 SWALL:CARB_ECOLI (SWALL:P00968) (1072 aa) fasta scores: E(): 0, 93.56% id in 1072 aa; Belongs to the CarB family. | Putative dihydrourdine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | 0.425 |
| carB | ftsI | ECA3870 | ECA3821 | Similar to Escherichia coli carbamoyl-phosphate synthase large chain CarB or PyrA or b0033 SWALL:CARB_ECOLI (SWALL:P00968) (1072 aa) fasta scores: E(): 0, 93.56% id in 1072 aa; Belongs to the CarB family. | Peptidoglycan synthetase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | 0.438 |
| carB | hslV | ECA3870 | ECA4261 | Similar to Escherichia coli carbamoyl-phosphate synthase large chain CarB or PyrA or b0033 SWALL:CARB_ECOLI (SWALL:P00968) (1072 aa) fasta scores: E(): 0, 93.56% id in 1072 aa; Belongs to the CarB family. | ATP-dependent protease (heat shock protein); Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.678 |
| carB | ilvC | ECA3870 | ECA4221 | Similar to Escherichia coli carbamoyl-phosphate synthase large chain CarB or PyrA or b0033 SWALL:CARB_ECOLI (SWALL:P00968) (1072 aa) fasta scores: E(): 0, 93.56% id in 1072 aa; Belongs to the CarB family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.473 |
| carB | sbcB | ECA3870 | ECA2565 | Similar to Escherichia coli carbamoyl-phosphate synthase large chain CarB or PyrA or b0033 SWALL:CARB_ECOLI (SWALL:P00968) (1072 aa) fasta scores: E(): 0, 93.56% id in 1072 aa; Belongs to the CarB family. | Similar to Escherichia coli exodeoxyribonuclease I SbcB or XonA or CpeA or b2011 SWALL:EX1_ECOLI (SWALL:P04995) (475 aa) fasta scores: E(): 6.8e-147, 73.26% id in 475 aa. | 0.677 |
| carB | uspA | ECA3870 | ECA0050 | Similar to Escherichia coli carbamoyl-phosphate synthase large chain CarB or PyrA or b0033 SWALL:CARB_ECOLI (SWALL:P00968) (1072 aa) fasta scores: E(): 0, 93.56% id in 1072 aa; Belongs to the CarB family. | Universal stress protein A; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri universal stress protein A UspA or b3495 or c4293 or z4895 or ecs4367 or sf3526 SWALL:USPA_ECOLI (SWALL:P28242) (143 aa) fasta scores: E(): 6.7e-47, 94.36% id in 142 aa. | 0.517 |
| carB | uspB | ECA3870 | ECA0049 | Similar to Escherichia coli carbamoyl-phosphate synthase large chain CarB or PyrA or b0033 SWALL:CARB_ECOLI (SWALL:P00968) (1072 aa) fasta scores: E(): 0, 93.56% id in 1072 aa; Belongs to the CarB family. | Similar to Yersinia pestis universal stress protein B UspB SWALL:Q8ZA50 (EMBL:AJ414160) (111 aa) fasta scores: E(): 3.4e-43, 84.68% id in 111 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 universal stress protein b UspB SWALL:USPB_ECOLI (SWALL:P37632) (111 aa) fasta scores: E(): 4.2e-40, 81.08% id in 111 aa. | 0.517 |
| dusB | carB | ECA0256 | ECA3870 | Putative dihydrourdine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | Similar to Escherichia coli carbamoyl-phosphate synthase large chain CarB or PyrA or b0033 SWALL:CARB_ECOLI (SWALL:P00968) (1072 aa) fasta scores: E(): 0, 93.56% id in 1072 aa; Belongs to the CarB family. | 0.425 |
| dusB | ftsI | ECA0256 | ECA3821 | Putative dihydrourdine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | Peptidoglycan synthetase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | 0.531 |
| dusB | hslV | ECA0256 | ECA4261 | Putative dihydrourdine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | ATP-dependent protease (heat shock protein); Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.529 |
| dusB | ilvC | ECA0256 | ECA4221 | Putative dihydrourdine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.574 |
| dusB | mviN | ECA0256 | ECA2521 | Putative dihydrourdine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | Putative virulence factor; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.576 |
| dusB | sbcB | ECA0256 | ECA2565 | Putative dihydrourdine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | Similar to Escherichia coli exodeoxyribonuclease I SbcB or XonA or CpeA or b2011 SWALL:EX1_ECOLI (SWALL:P04995) (475 aa) fasta scores: E(): 6.8e-147, 73.26% id in 475 aa. | 0.570 |
| dusB | uspA | ECA0256 | ECA0050 | Putative dihydrourdine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | Universal stress protein A; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri universal stress protein A UspA or b3495 or c4293 or z4895 or ecs4367 or sf3526 SWALL:USPA_ECOLI (SWALL:P28242) (143 aa) fasta scores: E(): 6.7e-47, 94.36% id in 142 aa. | 0.452 |
| ftsI | carB | ECA3821 | ECA3870 | Peptidoglycan synthetase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Similar to Escherichia coli carbamoyl-phosphate synthase large chain CarB or PyrA or b0033 SWALL:CARB_ECOLI (SWALL:P00968) (1072 aa) fasta scores: E(): 0, 93.56% id in 1072 aa; Belongs to the CarB family. | 0.438 |
| ftsI | dusB | ECA3821 | ECA0256 | Peptidoglycan synthetase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Putative dihydrourdine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | 0.531 |
| ftsI | hslV | ECA3821 | ECA4261 | Peptidoglycan synthetase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | ATP-dependent protease (heat shock protein); Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.498 |
| ftsI | ilvC | ECA3821 | ECA4221 | Peptidoglycan synthetase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.533 |
| ftsI | mviN | ECA3821 | ECA2521 | Peptidoglycan synthetase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Putative virulence factor; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.813 |
| ftsI | sbcB | ECA3821 | ECA2565 | Peptidoglycan synthetase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Similar to Escherichia coli exodeoxyribonuclease I SbcB or XonA or CpeA or b2011 SWALL:EX1_ECOLI (SWALL:P04995) (475 aa) fasta scores: E(): 6.8e-147, 73.26% id in 475 aa. | 0.531 |