STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sbcBSimilar to Escherichia coli exodeoxyribonuclease I SbcB or XonA or CpeA or b2011 SWALL:EX1_ECOLI (SWALL:P04995) (475 aa) fasta scores: E(): 6.8e-147, 73.26% id in 475 aa. (475 aa)    
Predicted Functional Partners:
ssb
Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
    
 
 0.698
recJ
Similar to Escherichia coli single-stranded-DNA-specific exonuclease RecJ SWALL:RECJ_ECOLI (SWALL:P21893) (577 aa) fasta scores: E(): 3.5e-163, 71.03% id in 580 aa, and to Erwinia chrysanthemi single-stranded-DNA-specific exonuclease RecJ SWALL:RECJ_ERWCH (SWALL:P39693) (575 aa) fasta scores: E(): 6.8e-178, 78.44% id in 580 aa.
    
 
 0.653
recB
Exodeoxyribonuclease V beta chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repai [...]
 
   
 0.592
rdgC
Recombination associated protein; May be involved in recombination; Belongs to the RdgC family.
  
     0.567
recC
Exodeoxyribonuclease V gamma chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repa [...]
  
   
 0.519
recQ
Similar to Escherichia coli ATP-dependent DNA helicase RecQ or b3822 SWALL:RECQ_ECOLI (SWALL:P15043) (607 aa) fasta scores: E(): 1.4e-198, 80.66% id in 605 aa.
      
 0.470
sbcC
Exonuclease; Similar to Escherichia coli exonuclease SbcC or RmuA or b0397 SWALL:SBCC_ECOLI (SWALL:P13458) (1048 aa) fasta scores: E(): 2.3e-52, 44.02% id in 1231 aa, and to Yersinia pestis ATP-dependent dsdna exonuclease SbcC or y0976 SWALL:AAM84557 (EMBL:AE013701) (1229 aa) fasta scores: E(): 2e-154, 50.04% id in 1233 aa.
  
   
 0.461
ECA1792
Similar to Yersinia pestis hypothetical protein ypo1594 or y1752 SWALL:Q8ZFU0 (EMBL:AJ414149) (174 aa) fasta scores: E(): 2.8e-56, 85.96% id in 171 aa, and to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 hypothetical protein yced or g30k or b1088 or c1358 or z1727 or ecs1466 SWALL:YCED_ECOLI (SWALL:P14189) (173 aa) fasta scores: E(): 1e-53, 79.76% id in 173 aa.
  
     0.448
sbcD
Exonuclease subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
  
   
 0.424
ECA2564
Similar to Yersinia pestis putative solute-binding iron ABC transport protein y4043 SWALL:AAM87587 (EMBL:AE014006) (329 aa) fasta scores: E(): 4.7e-74, 62.54% id in 315 aa, and to Brucella melitensis ferric anguibactin-binding protein bmeii0607 SWALL:Q8YCC5 (EMBL:AE009697) (293 aa) fasta scores: E(): 1.2e-49, 48.09% id in 289 aa.
       0.423
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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