STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ycgRConserved hypothetical protein; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility. (251 aa)    
Predicted Functional Partners:
flgM
Similar to Escherichia coli, and Shigella flexneri negative regulator of flagellin synthesis FlgM or b1071 or sf1077 SWALL:FLGM_ECOLI (SWALL:P43532) (97 aa) fasta scores: E(): 4.5e-14, 59.18% id in 98 aa.
 
  
 0.906
fliA
RNA polymerase sigma factor for flagellar operon; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.
 
  
 0.814
ECA1568
Putative chemotaxis signal transduction protein; Similar to Vibrio fischeri CheV SWALL:AAL86625 (EMBL:AY079167) (306 aa) fasta scores: E(): 1.6e-26, 34.36% id in 323 aa, and to Salmonella typhimurium putative chemotaxis signal transduction protein stm2314 SWALL:Q8ZNE6 (EMBL:AE008803) (333 aa) fasta scores: E(): 8.2e-81, 70.44% id in 318 aa.
 
  
 0.788
cheR
Chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
  
  
 0.780
motB
Chemotaxis protein; Similar to Escherichia coli, and Escherichia coli O157:H7 chemotaxis MotB protein MotB or b1889 or z2943 or ecs2599 SWALL:MOTB_ECOLI (SWALL:P09349) (308 aa) fasta scores: E(): 1.1e-64, 64.51% id in 310 aa.
 
 
 0.766
fliS
Flagellar protein; Similar to Salmonella typhimurium flagellar protein FliS or stm1961 SWALL:FLIS_SALTY (SWALL:P26609) (135 aa) fasta scores: E(): 1.4e-30, 69.85% id in 136 aa, and to Erwinia chrysanthemi FliS protein FliS SWALL:Q8RST3 (EMBL:AJ430202) (136 aa) fasta scores: E(): 4.4e-33, 73.52% id in 136 aa.
 
  
 0.756
flgK
Flagellar hook-associated protein 1; Similar to Salmonella typhimurium, and Salmonella typhi flagellar hook-associated protein 1 FlgK or FlaS or FlaW or stm1183 or sty1222 SWALL:FLGK_SALTY (SWALL:P15932) (552 aa) fasta scores: E(): 4.8e-81, 55.53% id in 569 aa.
 
  
 0.736
flgN
Flagella synthesis protein; Similar to Salmonella typhimurium, and Salmonella typhi flagella synthesis protein FlgN or stm1171 or sty1210 SWALL:FLGN_SALTY (SWALL:P37406) (140 aa) fasta scores: E(): 2.4e-14, 38.88% id in 144 aa, and to Yersinia enterocolitica flagella synthesis protein FlgN SWALL:FLGN_YEREN (SWALL:Q56854) (147 aa) fasta scores: E(): 6.2e-22, 46.85% id in 143 aa.
 
  
 0.719
motA
Chemotaxis protein; Similar to Escherichia coli chemotaxis MotA protein MotA or b1890 SWALL:MOTA_ECOLI (SWALL:P09348) (295 aa) fasta scores: E(): 1.5e-82, 72.54% id in 295 aa.
 
   0.709
fliM
Flagellar motor switch protein; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
 
 
 0.704
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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