STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
citESimilar to Klebsiella pneumoniae citrate lyase beta chain CitE SWALL:CILB_KLEPN (SWALL:P17725) (289 aa) fasta scores: E(): 1.3e-80, 72.56% id in 288 aa, and to Escherichia coli, and Escherichia coli O6 citrate lyase beta chain CitE or b0616 or c0706 SWALL:CILB_ECOLI (SWALL:P77770) (302 aa) fasta scores: E(): 2.7e-74, 65.17% id in 290 aa; Belongs to the HpcH/HpaI aldolase family. (291 aa)    
Predicted Functional Partners:
citF
Similar to Klebsiella pneumoniae citrate lyase alpha chain CitF SWALL:CILA_KLEPN (SWALL:P45413) (508 aa) fasta scores: E(): 1.3e-132, 67.52% id in 508 aa, and to Escherichia coli citrate lyase alpha chain citf or b0615 SWALL:CILA_ECOLI (SWALL:P75726) (510 aa) fasta scores: E(): 4.6e-131, 67.25% id in 510 aa.
 
 
 0.996
citD
Citrate lyase acyl carrier protein; Covalent carrier of the coenzyme of citrate lyase.
 
 
 0.995
citC
[citrate [pro-3s]-lyase] ligase; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase.
 
  
 0.989
ECA0824
Similar to Rhodospirillum rubrum pyruvate-flavodoxin oxidoreductase NifJ SWALL:NIFJ_RHORU (SWALL:Q53046) (1191 aa) fasta scores: E(): 0, 54.73% id in 1182 aa, and to Escherichia coli probable pyruvate-flavodoxin oxidoreductase ydbk or b1378 SWALL:NIFJ_ECOLI (SWALL:P52647) (1174 aa) fasta scores: E(): 0, 78.79% id in 1174 aa. Also similar to ECA2957 (47.377% id. in 1182 aa overlap).
  
 
 0.976
citX
Similar to Escherichia coli, and Escherichia coli O157:H7 apo-citrate lyase phosphoribosyl-dephospho-CoA transferase citx or b0614 or z0758 or ecs0653 SWALL:CITX_ECOLI (SWALL:P77563) (183 aa) fasta scores: E(): 6.7e-24, 40.85% id in 164 aa.
 
  
 0.976
citG
2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase; Catalyzes the formation of 2-(5''-triphosphoribosyl)-3'- dephosphocoenzyme-A, the precursor of the prosthetic group of the holo- acyl carrier protein (gamma chain) of citrate lyase, from ATP and dephospho-CoA; Belongs to the CitG/MdcB family.
 
  
 0.960
ECA4117
Similar to Klebsiella pneumoniae citrate lyase beta chain CitE SWALL:CILB_KLEPN (SWALL:P17725) (289 aa) fasta scores: E(): 4.4e-11, 30.13% id in 302 aa, and to Brucella melitensis citrate lyase beta chain bmeii1074 SWALL:Q8YB27 (EMBL:AE009739) (274 aa) fasta scores: E(): 1.3e-22, 40.71% id in 280 aa; Belongs to the HpcH/HpaI aldolase family.
  
  
 
0.958
fumA
Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
 0.805
citW
Similar to Klebsiella pneumoniae citrate/acetate antiporter CitW SWALL:Q8VS41 (EMBL:AF411142) (454 aa) fasta scores: E(): 1.9e-136, 76.75% id in 456 aa.
 
   
 0.795
maeB
Similar to Escherichia coli NADP-dependent malic enzyme MaeB or b2463 SWALL:MAO2_ECOLI (SWALL:P76558) (759 aa) fasta scores: E(): 0, 84.32% id in 759 aa.
  
 
 0.711
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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