STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ECA2575Putative fumarylacetoacetate hydrolase; Similar to Burkholderia cepacia DntG SWALL:Q8VUC7 (EMBL:AF169302) (281 aa) fasta scores: E(): 8.5e-37, 43.61% id in 282 aa, and to Salmonella typhimurium putative fumarylacetoacetate stm0331 SWALL:Q8ZRI8 (EMBL:AE008710) (292 aa) fasta scores: E(): 1.7e-68, 62.45% id in 285 aa. (294 aa)    
Predicted Functional Partners:
citW
Similar to Klebsiella pneumoniae citrate/acetate antiporter CitW SWALL:Q8VS41 (EMBL:AF411142) (454 aa) fasta scores: E(): 1.9e-136, 76.75% id in 456 aa.
 
     0.651
fumA
Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
  0.647
citE
Similar to Klebsiella pneumoniae citrate lyase beta chain CitE SWALL:CILB_KLEPN (SWALL:P17725) (289 aa) fasta scores: E(): 1.3e-80, 72.56% id in 288 aa, and to Escherichia coli, and Escherichia coli O6 citrate lyase beta chain CitE or b0616 or c0706 SWALL:CILB_ECOLI (SWALL:P77770) (302 aa) fasta scores: E(): 2.7e-74, 65.17% id in 290 aa; Belongs to the HpcH/HpaI aldolase family.
    
  0.624
aceB
Similar to Escherichia coli malate synthase A AceB or Mas or b4014 SWALL:MASY_ECOLI (SWALL:P08997) (533 aa) fasta scores: E(): 6.4e-180, 82.04% id in 529 aa.
  
 
 0.571
ECA1856
Putative FAD-binding oxidase; Similar to Yersinia pestis hypothetical protein ypo2407 or y1932 SWALL:AAM85498 (EMBL:AJ414152) (1018 aa) fasta scores: E(): 0, 82.41% id in 1018 aa, and to Escherichia coli hypothetical protein ydij or b1687 SWALL:YDIJ_ECOLI (SWALL:P77748) (1018 aa) fasta scores: E(): 0, 79.05% id in 1017 aa.
    
 0.550
citC
[citrate [pro-3s]-lyase] ligase; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase.
       0.549
ECA3947
Similar to Pseudomonas putida D-isomer specific 2-hydroxyacid dehydrogenase family protein pp4589 SWALL:AAN70162 (EMBL:AE016791) (310 aa) fasta scores: E(): 4.3e-61, 56.63% id in 309 aa, and to Pseudomonas aeruginosa probable 2-hydroxyacid dehydrogenase pa1296 SWALL:Q9I448 (EMBL:AE004559) (310 aa) fasta scores: E(): 5.3e-54, 51.94% id in 308 aa.
    
  0.516
citD
Citrate lyase acyl carrier protein; Covalent carrier of the coenzyme of citrate lyase.
       0.507
eda
Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri Khg/kdpg aldolase [includes: 4-hydroxy-2-oxoglutarate aldolase and 2- dehydro-3-deoxyphosphogluconate aldolase Eda or Hga or KdgA or b1850 or c2263 or z2902 or ecs2560 or sf1860 SWALL:ALKH_ECOLI (SWALL:P10177) (213 aa) fasta scores: E(): 1.2e-67, 89.15% id in 212 aa, and to Erwinia chrysanthemi khg/kdpg aldolase [includes: 4-hydroxy-2-oxoglutarate aldolase Eda or KdgA SWALL:ALKH_ERWCH (SWALL:P38448) (213 aa) fasta scores: E(): 7e-67, 89.2% id in 213 aa.
    
 0.506
aceA
Isocitrate lyase; Similar to Escherichia coli, and Escherichia coli O6 isocitrate lyase AceA or Icl or b4015 or c4972 SWALL:ACEA_ECOLI (SWALL:P05313) (434 aa) fasta scores: E(): 4.7e-157, 86.8% id in 432 aa.
     
  0.502
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.