STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (361 aa)    
Predicted Functional Partners:
serA
D-3-phosphoglycerate dehydrogenase; Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri D-3-phosphoglycerate dehydrogenase SerA or b2913 or c3494 or z4251 or ecs3784 or sf2898 SWALL:SERA_ECOLI (SWALL:P08328) (409 aa) fasta scores: E(): 4e-129, 82.72% id in 411 aa; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.974
pdxB
Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.
  
 0.964
serB
Phosphoserine phosphatase; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri phosphoserine phosphatase SerB or b4388 or z5989 or ecs5346 or sf4420 SWALL:SERB_ECOLI (SWALL:P06862) (322 aa) fasta scores: E(): 5.7e-81, 71.87% id in 320 aa.
  
 
 0.954
thrC
Threonine synthase; Similar to Escherichia coli threonine synthase ThrC or b0004 SWALL:THRC_ECOLI (SWALL:P00934) (428 aa) fasta scores: E(): 4.2e-135, 80.51% id in 426 aa.
   
 0.942
cysK
Cysteine synthase A; Similar to Escherichia coli, and Escherichia coli O157:H7 cysteine synthase A CysK or CysZ or b2414 or z3680 or ecs3286 SWALL:CYSK_ECOLI (SWALL:P11096) (322 aa) fasta scores: E(): 1.4e-100, 89.13% id in 322 aa; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.912
ECA1156
Similar to Yersinia pestis putative pyridoxal-phosphate dependent protein ypo3147 or y1037 SWALL:Q8ZC75 (EMBL:AJ414155) (346 aa) fasta scores: E(): 1.4e-117, 83.47% id in 345 aa, and to Salmonella typhimurium putative cysteine synthase/cystathionine beta-synthase stm0458 SWALL:Q8ZRB5 (EMBL:AE008717) (351 aa) fasta scores: E(): 1.6e-105, 76.38% id in 343 aa.
  
 
 0.912
pdxA
4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
     
 0.912
pheA
Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri P-protein [includes: chorismate mutase and prephenate dehydratase] PheA or b2599 or z3891 or ecs3462 or sf2659 SWALL:PHEA_ECOLI (SWALL:P07022) (386 aa) fasta scores: E(): 1e-115, 76.17% id in 382 aa.
  
  
 0.894
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
  
  
 0.861
tyrA
Similar to Escherichia coli T-protein [includes: chorismate mutase and prephenate dehydrogenase] TyrA or b2600 SWALL:TYRA_ECOLI (SWALL:P07023) (373 aa) fasta scores: E(): 1.6e-123, 87.13% id in 373 aa.
  
  
 0.776
Your Current Organism:
Pectobacterium atrosepticum
NCBI taxonomy Id: 218491
Other names: Erwinia carotovora subsp. atroseptica SCRI1043, Erwinia carotovora subsp. atroseptica str. SCRI1043, P. atrosepticum SCRI1043, Pectobacterium atrosepticum SCRI1043, Pectobacterium atrosepticum str. SCRI1043, Pectobacterium atrosepticum strain SCRI1043, Pectobacterium carotovora subsp. atroseptica SCRI1043, Pectobacterium carotovora subsp. atroseptica str. SCRI1043
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